ID R9NFP3_9FIRM Unreviewed; 499 AA.
AC R9NFP3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Glutamate synthase, NADH/NADPH, small subunit {ECO:0000313|EMBL:EOS82129.1};
GN ORFNames=C817_00044 {ECO:0000313|EMBL:EOS82129.1};
OS Dorea sp. 5-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS82129.1, ECO:0000313|Proteomes:UP000014211};
RN [1] {ECO:0000313|EMBL:EOS82129.1, ECO:0000313|Proteomes:UP000014211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5-2 {ECO:0000313|EMBL:EOS82129.1,
RC ECO:0000313|Proteomes:UP000014211};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Dorea bacterium 5-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS82129.1}.
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DR EMBL; ASTD01000001; EOS82129.1; -; Genomic_DNA.
DR RefSeq; WP_016169663.1; NZ_KE159715.1.
DR AlphaFoldDB; R9NFP3; -.
DR STRING; 1235798.C817_00044; -.
DR PATRIC; fig|1235798.3.peg.44; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_1_9; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000014211; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000014211}.
FT DOMAIN 24..137
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 153..479
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 499 AA; 55028 MW; A6BAF6DCF6418399 CRC64;
MGKATGFMEY GRQDKTAEEP EVRIRHFREF HTPLSREEQE RQGARCMACG VPFCQAGQMI
MGMASGCPLH NLVPEWNDLI YHGNWEEAYY RLKKTNNFPE FTSRVCPALC EAACTCSLSG
EAVSTKANEY GIIENAYEKG YAKARPVKIR TGKKVAVVGS GPSGLAAADM LNRRGHSVTV
FEREDKIGGL LRYGIPNMKL EKQIIDRKLA VMEEEGVTFV TGCNIGKDRK ASELLKEFDR
VILCCGASDP RDIKVPGRDA AGIYFAVDFL KSTTKALWEN EMQLKDGTYI SAKGKRVMVI
GGGDTGNDCV GTAMRHGAKS VLQVEMMPKA PDERAETNPW PEWPRVCKTD YGQAEAAAVF
GKDPRVYQTT VKEFKKDKAG NVCGAVLVKL ESKKDEKTGR MRMAEAAGSE YTAEVDLVLI
AAGFLGSESY VTKAFGVRVN ERSNVDTLSG AYHTNVEHVF AAGDMHRGQS LVVWAIREGR
EAAQEVDISL MGYTNMNIQ
//
