ID R9NP56_9FIRM Unreviewed; 431 AA.
AC R9NP56;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Sensor histidine kinase NatK C-terminal domain-containing protein {ECO:0000259|Pfam:PF14501};
GN ORFNames=C817_00511 {ECO:0000313|EMBL:EOS81782.1};
OS Dorea sp. 5-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS81782.1, ECO:0000313|Proteomes:UP000014211};
RN [1] {ECO:0000313|EMBL:EOS81782.1, ECO:0000313|Proteomes:UP000014211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5-2 {ECO:0000313|EMBL:EOS81782.1,
RC ECO:0000313|Proteomes:UP000014211};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Dorea bacterium 5-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS81782.1}.
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DR EMBL; ASTD01000006; EOS81782.1; -; Genomic_DNA.
DR AlphaFoldDB; R9NP56; -.
DR STRING; 1235798.C817_00511; -.
DR PATRIC; fig|1235798.3.peg.547; -.
DR eggNOG; COG0642; Bacteria.
DR HOGENOM; CLU_020211_13_1_9; -.
DR OrthoDB; 9816523at2; -.
DR Proteomes; UP000014211; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014211};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 328..426
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 431 AA; 50226 MW; FB58B04F52AAC73F CRC64;
MEGVPQGEGV MWIYRVMDIL GTLGDVIALG FIMTGICKEN RNKYVKYLPC VLFFCFVYMW
TWVIRDQTFK MPAIIIAGTV FIKLCYRDKW FNGIICMFLL YAEIILGETI AGSILSHFFD
PLTVKIGNEI FMRWQTYFGF FIVMLLLSFG ISRLFRNFQY ETTLKDFILI FVSYIFLIII
FLDDITIKSG NYNLEHHIMS SALAIIFTVQ LLYMKNYTLL KKVEQQEQFT IERMKEQFAY
YREKEDDEKR VRALYHDMKN HLLILERQNS AETKQMVSDL RRRISDYEEY IHTGNEFLDV
IIHDKAKKAK EQQIDFSAVL HFEDGGFIEP MDLSTIFGNA LDNAIEASVK LPPEQRLITV
KARSIHDVLM IVFENHAAAG RMNGTSKEDG FLHGFGIPNI QKAVEKYNGE CVIRQEDGKF
VMKNIIPLPE T
//
