ID R9PCT8_PSEHS Unreviewed; 1795 AA.
AC R9PCT8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Myosin heavy chain {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHSY_006659 {ECO:0000313|EMBL:GAC99062.1};
OS Pseudozyma hubeiensis (strain SY62) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Pseudozyma.
OX NCBI_TaxID=1305764 {ECO:0000313|EMBL:GAC99062.1, ECO:0000313|Proteomes:UP000014071};
RN [1] {ECO:0000313|Proteomes:UP000014071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY62 {ECO:0000313|Proteomes:UP000014071};
RX PubMed=23814110; DOI=10.1128/genomea.00409-13;
RA Konishi M., Hatada Y., Horiuchi J.;
RT "Draft genome sequence of the basidiomycetous yeast-like fungus Pseudozyma
RT hubeiensis SY62, which produces an abundant amount of the biosurfactant
RT mannosylerythritol lipids.";
RL Genome Announc. 1:E0040913-E0040913(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DF238822; GAC99062.1; -; Genomic_DNA.
DR RefSeq; XP_012192649.1; XM_012337259.1.
DR STRING; 1305764.R9PCT8; -.
DR GeneID; 24111928; -.
DR eggNOG; KOG0161; Eukaryota.
DR HOGENOM; CLU_000192_7_16_1; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000014071; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000014071}.
FT DOMAIN 22..71
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 75..811
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 689..711
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1614..1664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1763..1795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 882..1063
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1096..1400
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1433..1464
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1500..1563
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1695..1750
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1620..1664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1795 AA; 202235 MW; 6ABAF2B650A271A3 CRC64;
MPRPSRGVGQ SASDAASAAE FAAKKYVWIP DPNVGYLSAW VIKEEGDQSL CALQDGSNRT
VPTFELSKMN PPKFDKVEDI ADLTFLNEAS VVHNLRQRYF SSLIYTYSGL FLVAVNPYRS
LPIYTDAIVA AYKGRRREEN APHVFALADE AMRNMIDNRE NQSLLVTGES GAGKTENTKK
VIQYLAAIAA DPAAHGSQSP ANSLTPSSSR EVLDRINGVQ PVASKRLGLL ERQILQANPI
LEAFGNAQTI RNNNSSRFGK FVRIEFTSVG AIAGANIDWY LLEKSRVAIR SENERSFHIF
YQLLRGAEPE LKQKLLLTSS ADDYAYLKGT RKHVEGVDDN AEWKLLRDAL NTVGFTPEEQ
LNLFRVAAAI LHIGNIQLAT DRSEQARITN MPQVEKICHV LGLPQQEFAN ALLRPRVKAG
REWVTSARTM RQVSEEMAAL SKTLYEKAFG WLVDRINKAL DRPTSKSSFI GVLDIAGFEI
FDVNSFEQLC INYTNEKLQQ FFNHHMFVLE QEEYARENIE WDFVNFGLDL QPTIDLIEST
TPIGILSCLD EECIMPKATD LTFTEKLNRT WGTNKDGSAM DAAGAAMAAE KGLAHGSTKF
GRTRFASGFV VKHYAGDVEY RTDGWLDKNK DPLNDNLTRV MSESSDRFIA SLFAEYAEVD
EETSLASAPR RRVKRGAFRT VGQRHKEQLN SLMAQLSSTQ PHFVRCIVPN PEKKPGKMDV
PLVLEQLRCN GVLEGIRIAR LGYPNRLLFS EFRNRYEVLT PGIIPPGYMD GRKACQRMVE
SLELDKSTFK IGTSKVFFKA GVLAEMEERR DSHLYDIFSR FGAACRMYTA RRQMKKILNR
AAAVRTVQRN ARLYVELREW PWWQLYTRVR PLLTATRHDE ELKRKQLELA MVTERAERDQ
KEREALEALK FQLESEKRKI EEQLQSERTL LLDKDQVLAR SKERESALED DLAALQGDVD
LLEGQLEKAL ASQRATEQAH AELKQAFDQA ADHLLRLEAE QKAWKQKEDT FMRDLSTHST
NAEQFRSERQ AFAAERDDLS RKLQEKEQDV DRAHKRMLAA VQEVEAKLLA EANGRQEEQK
RALQLEDQSR QSSYQLSELQ RVAASHETRV KDKEQEVGQL QKQVSDLSRE RESLTKQLEE
LGLKLNTLTF DVNSVKDEHA KTSEARAALQ RELDETRRLM EAKSSEDVKT KEVHRMKEQE
LQTLREQMAS VQRELSESKH SSLEQISALR AEISAAQKEA QSHGAARQGA EVQVRDAEVR
VREADAKIAA AEKAKREAEA KLQEAQSKSA VINRGLQDAL KNKDMLEKQL AASATKHQDL
EDALLELERN EANWKHKADQ VAVELSTESK RRELLEQAHK QAERNANSLQ QLVAGKDKEI
SGLKHELTLV QQEMRKLQSM QNKTIVEHVH VLEEAKKYTD RQLADAQSKL QELAHYTKTL
EKSKTRLANE NEDLTREVTR LQRAAGGAVA ASPTVGNGLR GAVTTYGNVA PSANGDAKSV
KKLEDKVAEL TSSLKQAQQQ RDEALSNARR KDLQADEMVS RTRRQFETHI QELERQLKNS
QIARSTTMTN LEELILAGHG SPQVTGGSSD GLRHQILDEL RRGHEELEQD IAAKSDLLRN
HKTAPTNGIS APTRGSSSYY VYDKPRSNHA SNGSSSSSNT SDLETKLAEM TRAYNESLSN
QRSTQTQMAS LVTQIRDLQS GLDESELKYD QLAAAYQSLI QEAGVDEGMI ESLQSTLEKY
KSQADKHMES WRSSTMELER QAKSLKSSVG RGRGGSVVGE MNAMGSPSRS ALSMR
//
