ID R9PGM2_AGAAL Unreviewed; 343 AA.
AC R9PGM2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN ORFNames=AALB_0448 {ECO:0000313|EMBL:GAD00368.1};
OS Agarivorans albus MKT 106.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Agarivorans.
OX NCBI_TaxID=1331007 {ECO:0000313|EMBL:GAD00368.1, ECO:0000313|Proteomes:UP000014461};
RN [1] {ECO:0000313|EMBL:GAD00368.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Yasuike M., Nakamura Y., Kai W., Fujiwara A., Fukui Y., Satomi M., Sano M.;
RT "Draft Genome Sequence of Agarivorans albus Strain MKT 106T, an Agarolytic
RT Marine Bacterium.";
RL Genome Announc. 1:e00367-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC {ECO:0000256|ARBA:ARBA00043995}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD00368.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BARX01000002; GAD00368.1; -; Genomic_DNA.
DR RefSeq; WP_016400136.1; NZ_BARX01000002.1.
DR AlphaFoldDB; R9PGM2; -.
DR STRING; 1331007.AALB_0448; -.
DR OrthoDB; 9797795at2; -.
DR Proteomes; UP000014461; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002201; Glyco_trans_9.
DR InterPro; IPR011910; RfaF.
DR NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR Pfam; PF01075; Glyco_transf_9; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:GAD00368.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014461};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:GAD00368.1}.
SQ SEQUENCE 343 AA; 38233 MW; 95834AF79EC91838 CRC64;
MKILVVGPSW VGDMVMSQSL YKTLKQLHPK AQLDVLAPDW CRPMLERMPE VDNALRMPLG
HGDLQLTTRW KLARELKQNH YDWAITQPNS LKSALIPWLA GIKQRTGWKG ESRYGLLNDL
RSNKHDFPLM VERYVSLAHP KASMQSAADL PTYLHPQLQA NQANQQEALA QLALDTQHPI
LALCPGAEFG PAKRWPEQHY AQVAAHWINE RKGQVWIFGS DKDQTVGAQI ISHVPQELQP
YCHNLAGKTK LAEAIDLMAL ATLAVSNDSG LMHIAAALEL PLIAIYGSSS PKYTPPLTEN
AAILHTDIDC RPCFKKTCQF GHLKCLTELA PERAISSIAD LLT
//
