ID R9PPL6_AGAAL Unreviewed; 1051 AA.
AC R9PPL6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN ORFNames=AALB_3364 {ECO:0000313|EMBL:GAD03284.1};
OS Agarivorans albus MKT 106.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Agarivorans.
OX NCBI_TaxID=1331007 {ECO:0000313|EMBL:GAD03284.1, ECO:0000313|Proteomes:UP000014461};
RN [1] {ECO:0000313|EMBL:GAD03284.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Yasuike M., Nakamura Y., Kai W., Fujiwara A., Fukui Y., Satomi M., Sano M.;
RT "Draft Genome Sequence of Agarivorans albus Strain MKT 106T, an Agarolytic
RT Marine Bacterium.";
RL Genome Announc. 1:e00367-13(2013).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU364070}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU364070}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942,
CC ECO:0000256|RuleBase:RU364070}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD03284.1}.
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DR EMBL; BARX01000025; GAD03284.1; -; Genomic_DNA.
DR RefSeq; WP_016403051.1; NZ_BARX01000025.1.
DR AlphaFoldDB; R9PPL6; -.
DR STRING; 1331007.AALB_3364; -.
DR OrthoDB; 5833256at2; -.
DR Proteomes; UP000014461; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF78; CATION OR DRUG EFFLUX SYSTEM PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW Cell membrane {ECO:0000256|RuleBase:RU364070};
KW Membrane {ECO:0000256|RuleBase:RU364070};
KW Reference proteome {ECO:0000313|Proteomes:UP000014461};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364070};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364070}; Transport {ECO:0000256|RuleBase:RU364070}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1051
FT /note="Efflux pump membrane transporter"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004488102"
FT TRANSMEM 344..360
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 367..388
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 435..459
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 471..498
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 533..552
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 867..887
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 894..914
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 920..944
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 965..986
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 998..1024
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
SQ SEQUENCE 1051 AA; 113552 MW; 2515FB973D39A7C1 CRC64;
MVKFFISRPK TAIVLSVIMS VLGALAAYTM PVGQYPDVAP PMINVFTQYN GANSSVVNDT
VASVIEKEVN GVEGMIYMKS TSSNDGSYNL NVTFETGFDA DRAATLVQNR VNAAQPLLPD
EVKRSGIYVE KLSPSMLMIA SLNSKTGAHG TLELSYYLTG IVRETLSRIK GVSKVTPLGE
KEYAMRVWLE PERLQALDLT VNDISTAIAD QNAVRGAGSV GAEPVTGNND WQYTVQVRGR
LANEQAFGNI RVKAYPDGTL VRLKDVARIE LGAQKYLVDT YLNNQESVAM MIYQDPTANA
MQVAEDVRAA MAKLEQSLPN GMVFSLPYDA TEFIDVSIYN VQETLVIALI LVTLVTYLFL
QTWQATLIPA IAIPVSLIAT FAVMKAFGST INTISLFGLV LAIGVVVDAA IVVIENVERL
LHETTKPVKE CVEIAMNEVI GPCIAAAAVL LAVFGPTLVM PGMVGIIYAE FGIAISVSVV
ISTLVAMTLT PALCVMLMNR DLKPNRFFQA FNRGFERFTE LFGKGVAVLC RRVGIAVLLF
SVFLGTCAYL GASLPGGFLP DEDQGTFFAV VDLPEGAALN RTRDMTKLLV ESLADDPDIE
MAFSAAGYNL LNESSNSNSA LLVFSLKHWD QRSDKQQHQD QVIARVQAAI DALPEGVGFA
FGLPAIPALG MVNGFEFVLK DEMGKGPEKT AEVLEQLLDK ANQREEIASA FSTFSISMPN
LYLDINEEQA AAMGVAFGDI VNTLNVQYGG SYINDFTKGG RNYRVMLQAE ADSRQQIDDL
SNLYVRSSQG EMVRLSNLVS VRTVLNPSSL VRYNVSGSTT INGITMPGYS SGQAIAAMEQ
LANEVLPTGF SYEWTGLTLQ EQQAGNASLI AFAFAMLFTY LFLVAQYESW LTPLAILLAV
PTAIFGVLSA VLLSGTTINL YSQIAIMLLI GMASRNAILI VEFAKQLREQ KGYSIVEAGV
AAAKLRFRAV LMTAFSFILG VVPLMLASSA GAAAMQAIGM ASFGGMLAAT VLGCLFVPAF
FVLFQTLRER FSSKKQPEPE LLIATFPASN D
//
