ID R9PTD5_AGAAL Unreviewed; 370 AA.
AC R9PTD5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Thiazole biosynthesis protein ThiH {ECO:0000313|EMBL:GAD02231.1};
GN ORFNames=AALB_2311 {ECO:0000313|EMBL:GAD02231.1};
OS Agarivorans albus MKT 106.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Agarivorans.
OX NCBI_TaxID=1331007 {ECO:0000313|EMBL:GAD02231.1, ECO:0000313|Proteomes:UP000014461};
RN [1] {ECO:0000313|EMBL:GAD02231.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Yasuike M., Nakamura Y., Kai W., Fujiwara A., Fukui Y., Satomi M., Sano M.;
RT "Draft Genome Sequence of Agarivorans albus Strain MKT 106T, an Agarolytic
RT Marine Bacterium.";
RL Genome Announc. 1:e00367-13(2013).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD02231.1}.
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DR EMBL; BARX01000014; GAD02231.1; -; Genomic_DNA.
DR RefSeq; WP_016401999.1; NZ_BARX01000014.1.
DR AlphaFoldDB; R9PTD5; -.
DR STRING; 1331007.AALB_2311; -.
DR OrthoDB; 9801120at2; -.
DR Proteomes; UP000014461; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR012726; ThiH.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR02351; thiH; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF1; 2-IMINOACETATE SYNTHASE; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00301; 2-iminoacetate_synthase_(ThiH); 1.
DR SFLD; SFLDG01081; cleavage_of_the_Ca-Cb_bond_in; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014461};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 70..314
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 370 AA; 42464 MW; DF4143AC42DEABC5 CRC64;
MSFAEHLARY DNTAVHMAIN SKTAADVERA LAKDKLDLDD FQALISPAAE AYIELMAQRS
MRLTQQRFGK TQQFYIPLYL SNMCSNVCDY CGFSMGNKIR RVTLDMAQLD AELEAIKQLG
FDHILLVTGE SERKVGMDYF REVLPRIKAR FSHVSMEVQP LEQDEYEELI SLGLDAVMVY
QETYNRHRYA EVHPKGKKRD FDFRLATPER LGEAGIRKMG IGALIGLDEW RSDCFYVAAH
LQYLERKYWR SKFSISFPRL RPCEGGFQPK SVMTDKQLVQ LICAYRLFNP DVELSLSTRE
SEHFRNHAIP LGITSMSAFS STQPGGYADD STKALEQFEI SDERRPEVVA DAVKQAGYQV
VWKDWDRVLG
//
