ID R9T707_METII Unreviewed; 258 AA.
AC R9T707;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase {ECO:0000313|EMBL:AGN25456.1};
GN ORFNames=MMINT_00400 {ECO:0000313|EMBL:AGN25456.1};
OS Methanomassiliicoccus intestinalis (strain Issoire-Mx1).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
OC Methanomassiliicoccales; Methanomassiliicoccaceae; Methanomassiliicoccus.
OX NCBI_TaxID=1295009 {ECO:0000313|EMBL:AGN25456.1, ECO:0000313|Proteomes:UP000014070};
RN [1] {ECO:0000313|EMBL:AGN25456.1, ECO:0000313|Proteomes:UP000014070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Issoire-Mx1 {ECO:0000313|EMBL:AGN25456.1,
RC ECO:0000313|Proteomes:UP000014070};
RX PubMed=23846268; DOI=10.1128/genomeA.00453-13;
RA Borrel G., Harris H.M., Parisot N., Gaci N., Tottey W., Mihajlovski A.,
RA Deane J., Gribaldo S., Bardot O., Peyretaillade E., Peyret P.,
RA O'Toole P.W., Brugere J.F.;
RT "Genome sequence of 'Candidatus Methanomassiliicoccus intestinalis'
RT Issoire-Mx1, a third thermoplasmatales-related methanogenic archaeon from
RT human feces.";
RL Genome Announc. 1:142-142(2013).
CC -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00010398}.
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DR EMBL; CP005934; AGN25456.1; -; Genomic_DNA.
DR RefSeq; WP_020447981.1; NC_021353.1.
DR AlphaFoldDB; R9T707; -.
DR STRING; 1295009.MMINT_00400; -.
DR GeneID; 41322486; -.
DR KEGG; mer:MMINT_00400; -.
DR HOGENOM; CLU_070996_0_0_2; -.
DR InParanoid; R9T707; -.
DR OrthoDB; 375447at2157; -.
DR Proteomes; UP000014070; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR InterPro; IPR000489; Pterin-binding_dom.
DR PANTHER; PTHR45833:SF2; BIFUNCTIONAL HOMOCYSTEINE S-METHYLTRANSFERASE_5,10-METHYLENETETRAHYDROFOLATE REDUCTASE; 1.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR Pfam; PF00809; Pterin_bind; 1.
DR SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR PROSITE; PS50972; PTERIN_BINDING; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AGN25456.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014070};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AGN25456.1}.
FT DOMAIN 1..246
FT /note="Pterin-binding"
FT /evidence="ECO:0000259|PROSITE:PS50972"
SQ SEQUENCE 258 AA; 28221 MW; 6D0AB2205EFB24F3 CRC64;
MFIISERING QFISVGKAID NRDSKFIQEL ALKQVDSGAQ ALDVNVGPGR DNGPEDMTWL
VSTVQEVTEV PLCIDAFGPK TMEAGVKACN NPIIMNSTNA DPARMEKYFP ICREYNADII
CLCMDEKGIP NSADARAEMA MLMMATAMEY EIMPDRLFLD PLVMPVCAAQ DQCAKVIQAV
SMFQSLNEPA PRTVVGLSNV SNGAKNRSLI NTTYLAMLMG AGLSSAIMDP EDKELMDALK
AGEILLNRSL YCDDFLRA
//
