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Database: UniProt
Entry: REC10_SCHPO
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ID   REC10_SCHPO             Reviewed;         791 AA.
AC   Q09823;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   07-APR-2021, entry version 113.
DE   RecName: Full=Meiotic recombination protein rec10;
GN   Name=rec10; ORFNames=SPAC25G10.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7586030; DOI=10.1007/bf00311213;
RA   Lin Y., Smith G.R.;
RT   "Molecular cloning of the meiosis-induced rec10 gene of Schizosaccharomyces
RT   pombe.";
RL   Curr. Genet. 27:440-446(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Involved primarily in the early steps of meiotic
CC       recombination localized to chromosome III.
CC   -!- DEVELOPMENTAL STAGE: Most abundant at 2 hours after induction of
CC       meiosis, at the time of premeiotic DNA synthesis. Found at much lower
CC       levels before and after this time.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA99538.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U09871; AAA99538.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CU329670; CAA94633.1; -; Genomic_DNA.
DR   PIR; S55725; S55725.
DR   PIR; T52489; T52489.
DR   RefSeq; NP_594524.1; NM_001019953.2.
DR   BioGRID; 278184; 18.
DR   STRING; 4896.SPAC25G10.04c.1; -.
DR   PaxDb; Q09823; -.
DR   PRIDE; Q09823; -.
DR   EnsemblFungi; SPAC25G10.04c.1; SPAC25G10.04c.1:pep; SPAC25G10.04c.
DR   GeneID; 2541688; -.
DR   KEGG; spo:SPAC25G10.04c; -.
DR   PomBase; SPAC25G10.04c; rec10.
DR   VEuPathDB; FungiDB:SPAC25G10.04c; -.
DR   HOGENOM; CLU_354176_0_0_1; -.
DR   OMA; HRDFACR; -.
DR   PRO; PR:Q09823; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0000785; C:chromatin; IDA:PomBase.
DR   GO; GO:0030998; C:linear element; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; IMP:PomBase.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
DR   InterPro; IPR012491; Red1/Rec10.
DR   Pfam; PF07964; Red1; 1.
PE   2: Evidence at transcript level;
KW   Meiosis; Reference proteome.
FT   CHAIN           1..791
FT                   /note="Meiotic recombination protein rec10"
FT                   /id="PRO_0000097220"
FT   CONFLICT        202
FT                   /note="S -> F (in Ref. 1; AAA99538)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        257
FT                   /note="S -> A (in Ref. 1; AAA99538)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   791 AA;  89876 MW;  682DFA66B5FFA7B9 CRC64;
     MDIFSEFLNC LSSDGTLNES SIYKTYQILE SLNPKDVDTK ENYIKLSNTF STLGSGVGFQ
     DNLLIEMFKI LTVLFFKTRS TDLGDLLIES FTSLEIEKLM RVKKTIGSIV LTKGIQELQE
     IELPKVGFNC MTYDESIFQG ISLERLILQL MSIFIAKCEE NKLWLVNNRK DLDLRVIGQR
     LLHRDFACRF LSGLFISRFS VSGDTDESKH QNGIRLQLFI DFSKFETRLT MQILKADRIF
     STCVANTVHA YEGLFSSGSN IDSTIATLVL EPRDLIVYRK GFALLQIPWT SVTTIDKIKK
     VKSLKIITEV SSLDEFVFQC KDGDKFDELF STSEEIMNKL LPAIIVSPKL TLRNRSIIQI
     KEGESKLPNT SKQASQNLPH LDDELAYQRF EDQVIDKSVC DDECTNTENT PSSNIPADVK
     DSLSADDYAY DTKRKTQIED LEEDQNKSKI ASKDGTNLKE INSVPEFSDE NVINQTGPAK
     KTPVQRRKDG KFAKSTKRKK QKSLKPDTEN QESSVKNKKA KSNVNLQYSP KTPICKINDE
     TLKPPTIANI AGHKQMNHLT SENIETPVPV PNGNWYNGVK HETATDIFTT CHDGNNSLKS
     SVWKELLKEK HWKQESKPQL TGNSRQIDLS TFVKQANTPN ITSLLDGTCS SPPNNECFND
     KEPDSSSSTL ISDRQELEYR NPNAETVKLE EIPYNKFFKT VEKNEAYNPS SKSATIDGLQ
     RYTSMIGNQI YEGILQNEKE LRSKLEAYHI NCNKVIKEFS KRQTARYKII EKELAQIEVN
     LVSQIDSLMF K
//
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