ID RETM_AEDAE Reviewed; 646 AA.
AC Q16KN5;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=Protein real-time;
GN Name=retm {ECO:0000250|UniProtKB:Q9VMD6}; ORFNames=AAEL012929;
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159;
RN [1] {ECO:0000312|EMBL:EAT34866.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVPib12;
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9VMD6}.
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DR EMBL; CH477949; EAT34866.1; -; Genomic_DNA.
DR RefSeq; XP_001663116.1; XM_001663066.1.
DR AlphaFoldDB; Q16KN5; -.
DR SMR; Q16KN5; -.
DR STRING; 7159.Q16KN5; -.
DR PaxDb; 7159-AAEL012929-PA; -.
DR EnsemblMetazoa; AAEL012929-RA; AAEL012929-PA; AAEL012929.
DR VEuPathDB; VectorBase:AAEL012929; -.
DR eggNOG; KOG1471; Eukaryota.
DR HOGENOM; CLU_023840_0_0_1; -.
DR InParanoid; Q16KN5; -.
DR OMA; QLMYFYE; -.
DR PhylomeDB; Q16KN5; -.
DR Proteomes; UP000008820; Chromosome 2.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR006797; PRELI/MSF1_dom.
DR PANTHER; PTHR23324:SF66; PROTEIN REAL-TIME; 1.
DR PANTHER; PTHR23324; SEC14 RELATED PROTEIN; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF03765; CRAL_TRIO_N; 1.
DR Pfam; PF04707; PRELI; 1.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50904; PRELI_MSF1; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome.
FT CHAIN 1..646
FT /note="Protein real-time"
FT /id="PRO_0000312682"
FT DOMAIN 2..175
FT /note="PRELI/MSF1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00158"
FT DOMAIN 294..471
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT DOMAIN 499..646
FT /note="GOLD"
FT /evidence="ECO:0000255"
SQ SEQUENCE 646 AA; 74377 MW; C9773F370A181413 CRC64;
MVQKYESPVR IYKYPFELVM AAYERRFPTC PQMPIVLDCE IIDDAETDNG AKRETKRRCK
LAVDAPYLFK KIIGIDVAYF IQTNFLDLKT RTLNIEAINE TFSSRIEIFE KCRYYAHPEN
PDWTCFDQVA TLDIKNFFGF EHSMEKMGMK QYSQTTQKGK EIIEYFINEL KKEGISHVDR
WKEDETTEPA ATATTTVSIS SEKPPLTRDN SILDADYIAT YLGQLSPLQE SKLVQFRKKI
EETNHEGKVP DYQTLLRFLR ARDFSIEKAA SMLQESLQWR EEHRIDDILG EYKTPVVVEK
YFPGGWHHHD KDGRPLYILR LGNMDVKGLL KSVGEDELLK LTLHICEEGL KLMKEATKLF
GKPIWNWCLL VDLDGLSMRH LWRPGVKALL RIIETVEKNY PETMGRVLIV RAPRVFPVLW
TIVSAFIDEN TRSKFLFFGG PDCLHIEDGL EHYIPTEKIP SFLGGSCITM IHEGGLIPKH
LYKSESVEEH NGVPHGHEHH GLYKSVDLKP GQMFELVIKN TDPKSVLTWD IDVLKNDILF
ALYRTDKDLE QSFNDSFSSV FDNADMKEGV HYTRLEEKVR CKPKEGVQGS HEMATAGTYV
LQWMCPPSCD GPAQLMYFHE ILSSANYKGS MTSLQSGFSS NSLQSR
//
