ID RL10_CHICK Reviewed; 210 AA.
AC Q08200;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Large ribosomal subunit protein uL16 {ECO:0000305};
DE AltName: Full=60S ribosomal protein L10 {ECO:0000305};
DE AltName: Full=Jun-binding protein JIF-1;
DE AltName: Full=Ribosomal protein L10 {ECO:0000250|UniProtKB:P27635};
DE Flags: Fragment;
GN Name=RPL10 {ECO:0000250|UniProtKB:P27635}; Synonyms=JIF1;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION (MICROBIAL INFECTION).
RX PubMed=8341691; DOI=10.1073/pnas.90.14.6726;
RA Monteclaro F.S., Vogt P.K.;
RT "A Jun-binding protein related to a putative tumor suppressor.";
RL Proc. Natl. Acad. Sci. U.S.A. 90:6726-6730(1993).
CC -!- FUNCTION: Component of the large ribosomal subunit. Plays a role in the
CC formation of actively translating ribosomes.
CC {ECO:0000250|UniProtKB:P27635}.
CC -!- FUNCTION: (Microbial infection) Seems to bind to the leucine zipper of
CC viral and cellular JUN. {ECO:0000305|PubMed:8341691}.
CC -!- SUBUNIT: Component of the large ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (28S, 5.8S and 5S). {ECO:0000250|UniProtKB:P27635}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6ZWV3}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL16 family.
CC {ECO:0000305}.
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DR EMBL; L13234; AAA48928.1; -; mRNA.
DR PIR; A48226; A48226.
DR AlphaFoldDB; Q08200; -.
DR SMR; Q08200; -.
DR PaxDb; 9031-ENSGALP00000042855; -.
DR eggNOG; KOG0857; Eukaryota.
DR InParanoid; Q08200; -.
DR PhylomeDB; Q08200; -.
DR Proteomes; UP000000539; Unassembled WGS sequence.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:AgBase.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR GO; GO:0045182; F:translation regulator activity; ISS:UniProtKB.
DR GO; GO:1990403; P:embryonic brain development; ISS:UniProtKB.
DR GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd01433; Ribosomal_L16_L10e; 1.
DR Gene3D; 3.30.60.300; -; 1.
DR Gene3D; 3.90.1170.10; Ribosomal protein L10e/L16; 1.
DR InterPro; IPR047873; Ribosomal_uL16.
DR InterPro; IPR018255; Ribosomal_uL16_CS_euk_arc.
DR InterPro; IPR016180; Ribosomal_uL16_dom.
DR InterPro; IPR001197; Ribosomal_uL16_euk_arch.
DR InterPro; IPR036920; Ribosomal_uL16_sf.
DR NCBIfam; TIGR00279; uL16_euk_arch; 1.
DR PANTHER; PTHR11726; 60S RIBOSOMAL PROTEIN L10; 1.
DR PANTHER; PTHR11726:SF10; 60S RIBOSOMAL PROTEIN L10; 1.
DR Pfam; PF00252; Ribosomal_L16; 1.
DR PIRSF; PIRSF005590; Ribosomal_L10; 1.
DR SUPFAM; SSF54686; Ribosomal protein L16p/L10e; 1.
DR PROSITE; PS01257; RIBOSOMAL_L10E; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Developmental protein; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Translation regulation.
FT CHAIN <1..210
FT /note="Large ribosomal subunit protein uL16"
FT /id="PRO_0000147111"
FT NON_TER 1
SQ SEQUENCE 210 AA; 23987 MW; 8CD3E67ED3B1F00F CRC64;
PRCYRYCKNK PYPKSRFCRG VPDPKIRIFD LGRKKAKVDE FPLCGHMVSD EYEQLSSEAL
EAARICANKY MVKSCGKDGF HIRVRLHPFH VIRINKMLSC AGADRLQTGM RGAFGKPQGT
VARVHMGQVI MSIRTKAQNK EHVVEALRRA KFKFPGRQKI HISKKWGFTK FNADAFEEMV
AQKRLIPDGC GVKYVPGRGP LDRWRALHAA
//
