ID RL19_CAEEL Reviewed; 198 AA.
AC O02639;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 27-MAR-2024, entry version 147.
DE RecName: Full=Large ribosomal subunit protein eL19 {ECO:0000305};
DE AltName: Full=60S ribosomal protein L19;
GN Name=rpl-19; ORFNames=C09D4.5;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL19 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO080461; CCD63892.1; -; Genomic_DNA.
DR PIR; T29135; T29135.
DR RefSeq; NP_491608.1; NM_059207.5.
DR AlphaFoldDB; O02639; -.
DR SMR; O02639; -.
DR BioGRID; 37659; 101.
DR DIP; DIP-25603N; -.
DR IntAct; O02639; 3.
DR STRING; 6239.C09D4.5.2; -.
DR iPTMnet; O02639; -.
DR EPD; O02639; -.
DR PaxDb; 6239-C09D4-5-1; -.
DR PeptideAtlas; O02639; -.
DR EnsemblMetazoa; C09D4.5.1; C09D4.5.1; WBGene00004431.
DR EnsemblMetazoa; C09D4.5.2; C09D4.5.2; WBGene00004431.
DR GeneID; 172201; -.
DR KEGG; cel:CELE_C09D4.5; -.
DR UCSC; C09D4.5.1; c. elegans.
DR AGR; WB:WBGene00004431; -.
DR WormBase; C09D4.5; CE08034; WBGene00004431; rpl-19.
DR eggNOG; KOG1696; Eukaryota.
DR GeneTree; ENSGT00390000012628; -.
DR HOGENOM; CLU_083919_0_1_1; -.
DR InParanoid; O02639; -.
DR OMA; NRVWIDP; -.
DR OrthoDB; 5483247at2759; -.
DR PhylomeDB; O02639; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR SignaLink; O02639; -.
DR PRO; PR:O02639; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00004431; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0008340; P:determination of adult lifespan; IMP:WormBase.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd01417; Ribosomal_L19e_E; 1.
DR Gene3D; 1.10.1200.240; -; 1.
DR Gene3D; 1.10.1650.10; -; 1.
DR HAMAP; MF_01475; Ribosomal_eL19; 1.
DR InterPro; IPR035970; 60S_ribosomal_eL19_sf.
DR InterPro; IPR039547; Ribosomal_eL19.
DR InterPro; IPR023638; Ribosomal_eL19_CS.
DR InterPro; IPR000196; Ribosomal_eL19_dom.
DR InterPro; IPR015972; Ribosomal_eL19_dom1.
DR InterPro; IPR033935; Ribosomal_eL19_euk.
DR PANTHER; PTHR10722; 60S RIBOSOMAL PROTEIN L19; 1.
DR PANTHER; PTHR10722:SF0; 60S RIBOSOMAL PROTEIN L19; 1.
DR Pfam; PF01280; Ribosomal_L19e; 1.
DR SMART; SM01416; Ribosomal_L19e; 1.
DR SUPFAM; SSF48140; Ribosomal protein L19 (L19e); 1.
DR PROSITE; PS00526; RIBOSOMAL_L19E; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..198
FT /note="Large ribosomal subunit protein eL19"
FT /id="PRO_0000131176"
FT REGION 66..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 23652 MW; 03876B70136D0479 CRC64;
MSNLRLQKRL ASAVLKCGKH RVWLDPNEVS EISGANSRQS IRRLVNDGLI IRKPVTVHSR
FRAREYEEAR RKGRHTGYGK RRGTANARMP EKTLWIRRMR VLRNLLRRYR DAKKLDKHLY
HELYLRAKGN NFKNKKNLIE YIFKKKTENK RAKQLADQAQ ARRDKNKESR KRREERQVVK
RAELLRKISQ SEKVIAGK
//
