ID RL1_PSEAE Reviewed; 231 AA.
AC Q9HWC6;
DT 25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE RecName: Full=Large ribosomal subunit protein uL1 {ECO:0000255|HAMAP-Rule:MF_01318};
DE AltName: Full=50S ribosomal protein L1 {ECO:0000305};
GN Name=rplA {ECO:0000255|HAMAP-Rule:MF_01318}; OrderedLocusNames=PA4273;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile in
CC the ribosome, and is involved in E site tRNA release.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it
CC controls the translation of the L11 operon by binding to its mRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01318}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
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DR EMBL; AE004091; AAG07661.1; -; Genomic_DNA.
DR PIR; B83111; B83111.
DR RefSeq; NP_252963.1; NC_002516.2.
DR RefSeq; WP_003093749.1; NZ_QZGE01000028.1.
DR AlphaFoldDB; Q9HWC6; -.
DR SMR; Q9HWC6; -.
DR STRING; 208964.PA4273; -.
DR PaxDb; 208964-PA4273; -.
DR DNASU; 881704; -.
DR GeneID; 77219188; -.
DR GeneID; 881704; -.
DR KEGG; pae:PA4273; -.
DR PATRIC; fig|208964.12.peg.4474; -.
DR PseudoCAP; PA4273; -.
DR HOGENOM; CLU_062853_0_0_6; -.
DR InParanoid; Q9HWC6; -.
DR OrthoDB; 9803740at2; -.
DR PhylomeDB; Q9HWC6; -.
DR BioCyc; PAER208964:G1FZ6-4348-MONOMER; -.
DR PRO; PR:Q9HWC6; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00403; Ribosomal_L1; 1.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 3.40.50.790; -; 1.
DR HAMAP; MF_01318_B; Ribosomal_uL1_B; 1.
DR InterPro; IPR005878; Ribosom_uL1_bac-type.
DR InterPro; IPR002143; Ribosomal_uL1.
DR InterPro; IPR023674; Ribosomal_uL1-like.
DR InterPro; IPR028364; Ribosomal_uL1/biogenesis.
DR InterPro; IPR016095; Ribosomal_uL1_3-a/b-sand.
DR InterPro; IPR023673; Ribosomal_uL1_CS.
DR NCBIfam; TIGR01169; rplA_bact; 1.
DR PANTHER; PTHR36427:SF3; 39S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR36427; 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL; 1.
DR Pfam; PF00687; Ribosomal_L1; 1.
DR PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR SUPFAM; SSF56808; Ribosomal protein L1; 1.
DR PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repressor; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Translation regulation; tRNA-binding.
FT CHAIN 1..231
FT /note="Large ribosomal subunit protein uL1"
FT /id="PRO_0000125714"
SQ SEQUENCE 231 AA; 24234 MW; A38C3FCA01E32905 CRC64;
MAKLTKRQKA IAEKVVAGKQ YSFEEAAKLL AELSTIKFKE SVDVAVNLGV DPRKSDQVVR
GATVLPNGTG KSVRVAVFTQ GPAAEAALAA GADKVGMDEL AAEMKGGDLN YDVVIASPDA
MRVVGQLGQI LGPRGLMPNP KVGTVTPDVA TAVKNAKAGQ VRFRTDKNGI IHSSVGKVDF
EPAKLQQNVE ALLADLKRLK PSSSKGVYVK RVTLSTTMGP GLQIDLASLE A
//
