ID RL1_THIDA Reviewed; 231 AA.
AC Q3SLQ9;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=Large ribosomal subunit protein uL1 {ECO:0000255|HAMAP-Rule:MF_01318};
DE AltName: Full=50S ribosomal protein L1 {ECO:0000305};
GN Name=rplA {ECO:0000255|HAMAP-Rule:MF_01318}; OrderedLocusNames=Tbd_0395;
OS Thiobacillus denitrificans (strain ATCC 25259).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Thiobacillaceae; Thiobacillus.
OX NCBI_TaxID=292415;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25259;
RX PubMed=16452431; DOI=10.1128/jb.188.4.1473-1488.2006;
RA Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W.,
RA Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.;
RT "The genome sequence of the obligately chemolithoautotrophic, facultatively
RT anaerobic bacterium Thiobacillus denitrificans.";
RL J. Bacteriol. 188:1473-1488(2006).
CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile in
CC the ribosome, and is involved in E site tRNA release.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it
CC controls the translation of the L11 operon by binding to its mRNA.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01318}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family.
CC {ECO:0000255|HAMAP-Rule:MF_01318}.
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DR EMBL; CP000116; AAZ96348.1; -; Genomic_DNA.
DR RefSeq; WP_011310908.1; NC_007404.1.
DR AlphaFoldDB; Q3SLQ9; -.
DR SMR; Q3SLQ9; -.
DR STRING; 292415.Tbd_0395; -.
DR KEGG; tbd:Tbd_0395; -.
DR eggNOG; COG0081; Bacteria.
DR HOGENOM; CLU_062853_0_0_4; -.
DR OrthoDB; 9803740at2; -.
DR Proteomes; UP000008291; Chromosome.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00403; Ribosomal_L1; 1.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 3.40.50.790; -; 1.
DR HAMAP; MF_01318_B; Ribosomal_uL1_B; 1.
DR InterPro; IPR005878; Ribosom_uL1_bac-type.
DR InterPro; IPR002143; Ribosomal_uL1.
DR InterPro; IPR023674; Ribosomal_uL1-like.
DR InterPro; IPR028364; Ribosomal_uL1/biogenesis.
DR InterPro; IPR016095; Ribosomal_uL1_3-a/b-sand.
DR InterPro; IPR023673; Ribosomal_uL1_CS.
DR NCBIfam; TIGR01169; rplA_bact; 1.
DR PANTHER; PTHR36427:SF3; 39S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR36427; 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL; 1.
DR Pfam; PF00687; Ribosomal_L1; 1.
DR PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR SUPFAM; SSF56808; Ribosomal protein L1; 1.
DR PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repressor; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Translation regulation; tRNA-binding.
FT CHAIN 1..231
FT /note="Large ribosomal subunit protein uL1"
FT /id="PRO_0000230647"
SQ SEQUENCE 231 AA; 24330 MW; FC66BB3E77A95FE1 CRC64;
MANVSKRLRA LKEKIDRSRN YPVVDALQLV KDSATAKFDE SIDVAVNLGV DARKSDQMVR
GAVVLPKGIG KTVRVAVFAQ GDNAQKARDA GADIVGFDDL AADIKAGKMD FDVVIATPDA
MRVVGQLGQI LGPRGLMPNP KVGTVSPDVV GAVKNAKAGQ VQYRTDKGGI VHCTIGRASF
SVDDLKENLV ALLDALQRAK PASSKGIYFK RLSVSSTMGV GVRVDQGSVA A
//
