ID RL3_FUSNN Reviewed; 211 AA.
AC Q8RIF5;
DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=Large ribosomal subunit protein uL3 {ECO:0000255|HAMAP-Rule:MF_01325};
DE AltName: Full=50S ribosomal protein L3 {ECO:0000305};
GN Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=FN1645;
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=190304;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC
RC 2640 / LMG 13131 / VPI 4355;
RX PubMed=11889109; DOI=10.1128/jb.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C.,
RA Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR EMBL; AE009951; AAL93760.1; -; Genomic_DNA.
DR RefSeq; NP_602461.1; NC_003454.1.
DR RefSeq; WP_011015720.1; NZ_CP028101.1.
DR AlphaFoldDB; Q8RIF5; -.
DR SMR; Q8RIF5; -.
DR STRING; 190304.FN1645; -.
DR PaxDb; 190304-FN1645; -.
DR EnsemblBacteria; AAL93760; AAL93760; FN1645.
DR GeneID; 79782583; -.
DR KEGG; fnu:FN1645; -.
DR PATRIC; fig|190304.8.peg.138; -.
DR eggNOG; COG0087; Bacteria.
DR HOGENOM; CLU_044142_4_1_0; -.
DR InParanoid; Q8RIF5; -.
DR BioCyc; FNUC190304:G1FZS-148-MONOMER; -.
DR Proteomes; UP000002521; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.160.810; -; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR HAMAP; MF_01325_B; Ribosomal_uL3_B; 1.
DR InterPro; IPR000597; Ribosomal_uL3.
DR InterPro; IPR019927; Ribosomal_uL3_bac/org-type.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR03625; L3_bact; 1.
DR PANTHER; PTHR11229:SF8; 39S RIBOSOMAL PROTEIN L3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11229; 50S RIBOSOMAL PROTEIN L3; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..211
FT /note="Large ribosomal subunit protein uL3"
FT /id="PRO_0000077102"
FT REGION 116..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 211 AA; 22631 MW; 5963F13CDE5E189B CRC64;
MSGILGKKIG MTQIFEDGKF VPVTVVEAGP NFVLQKKTEE KDGYVALQLG FDEKKEKNTT
KPLMGIFNKA GVKPQRFVKE LEVESVDGYE LGQEIKVDVL TEVGYVDITG TSKGKGTSGV
MKKHGFSGNR ASHGVSRNHR LGGSIGMSSW PGKVLKGKKM AGQHGNATVT VQNLKVVKVD
AEHNLLLIKG AVPGAKNSYL VIKPAVKKVI G
//
