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Database: UniProt
Entry: RL3_VIBCH
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Original site: RL3_VIBCH 
ID   RL3_VIBCH               Reviewed;         209 AA.
AC   Q9KNY4;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   24-JAN-2024, entry version 105.
DE   RecName: Full=Large ribosomal subunit protein uL3 {ECO:0000255|HAMAP-Rule:MF_01325};
DE   AltName: Full=50S ribosomal protein L3 {ECO:0000305};
GN   Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=VC_2596;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC       subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC       proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- PTM: Methylated by PrmB. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR   EMBL; AE003852; AAF95737.1; -; Genomic_DNA.
DR   PIR; F82059; F82059.
DR   RefSeq; NP_232224.1; NC_002505.1.
DR   RefSeq; WP_000579663.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KNY4; -.
DR   SMR; Q9KNY4; -.
DR   STRING; 243277.VC_2596; -.
DR   DNASU; 2615613; -.
DR   EnsemblBacteria; AAF95737; AAF95737; VC_2596.
DR   GeneID; 69718800; -.
DR   KEGG; vch:VC_2596; -.
DR   PATRIC; fig|243277.26.peg.2475; -.
DR   eggNOG; COG0087; Bacteria.
DR   HOGENOM; CLU_044142_4_1_6; -.
DR   OMA; KRMAGRY; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.160.810; -; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   HAMAP; MF_01325_B; Ribosomal_uL3_B; 1.
DR   InterPro; IPR000597; Ribosomal_uL3.
DR   InterPro; IPR019927; Ribosomal_uL3_bac/org-type.
DR   InterPro; IPR019926; Ribosomal_uL3_CS.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   NCBIfam; TIGR03625; L3_bact; 1.
DR   PANTHER; PTHR11229; 50S RIBOSOMAL PROTEIN L3; 1.
DR   PANTHER; PTHR11229:SF16; 50S RIBOSOMAL PROTEIN L3-1, CHLOROPLASTIC; 1.
DR   Pfam; PF00297; Ribosomal_L3; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE   3: Inferred from homology;
KW   Methylation; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..209
FT                   /note="Large ribosomal subunit protein uL3"
FT                   /id="PRO_0000077186"
FT   MOD_RES         150
FT                   /note="N5-methylglutamine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01325"
SQ   SEQUENCE   209 AA;  22359 MW;  C8306BC06945091F CRC64;
     MIGLIGRKVG MTRVFTEDGV SIPVTVVEVE ANRVSQVKTL ETDGYAAIQV TTGSKKANRV
     TKPEAGHFAK AGVEAGRGLW EFRLENGEEF AVGSELTVEL FNEVKKVDVT GTSKGKGFQG
     AVKRWNFRTQ DMTHGNSLSH RAPGSIGQCQ TPGRVFKGKK MAGHMGAERV TTQNLEIVRV
     DAERNLLLIK GAVPGATGGN VIVKPAVKA
//
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