ID   RLP24_DICDI             Reviewed;         164 AA.
AC   Q86B05; Q558U6;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   24-JAN-2024, entry version 106.
DE   RecName: Full=Probable ribosome biogenesis protein RLP24;
GN   Name=rlp24; ORFNames=DDB_G0272789;
OS   Dictyostelium discoideum (Social amoeba).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AX4;
RX   PubMed=15010511; DOI=10.1093/nar/gkh262;
RA   Urushihara H., Morio T., Saito T., Kohara Y., Koriki E., Ochiai H.,
RA   Maeda M., Williams J.G., Takeuchi I., Tanaka Y.;
RT   "Analyses of cDNAs from growth and slug stages of Dictyostelium
RT   discoideum.";
RL   Nucleic Acids Res. 32:1647-1653(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       Ensures the docking of nog1 to pre-60S particles. Activates and
CC       recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.
CC       {ECO:0000250|UniProtKB:Q07915}.
CC   -!- SUBUNIT: Associated with nucleolar and cytoplasmic pre-60S particles.
CC       At the end of biogenesis it dissociates from cytoplasmic pre-60S
CC       particles and is likely to be exchanged for its ribosomal homolog,
CC       RPL24. {ECO:0000250|UniProtKB:Q07915}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q07915}. Nucleus
CC       {ECO:0000250|UniProtKB:Q07915}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000250|UniProtKB:Q07915}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL24 family.
CC       {ECO:0000305}.
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DR   EMBL; AU266916; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BJ418184; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AAFI02000008; EAL71032.1; -; Genomic_DNA.
DR   RefSeq; XP_644970.1; XM_639878.1.
DR   AlphaFoldDB; Q86B05; -.
DR   SMR; Q86B05; -.
DR   STRING; 44689.Q86B05; -.
DR   PaxDb; 44689-DDB0234227; -.
DR   EnsemblProtists; EAL71032; EAL71032; DDB_G0272789.
DR   GeneID; 8618647; -.
DR   KEGG; ddi:DDB_G0272789; -.
DR   dictyBase; DDB_G0272789; rlp24.
DR   eggNOG; KOG1723; Eukaryota.
DR   HOGENOM; CLU_089419_2_0_1; -.
DR   InParanoid; Q86B05; -.
DR   OMA; GKEMIMD; -.
DR   PhylomeDB; Q86B05; -.
DR   PRO; PR:Q86B05; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; ISS:dictyBase.
DR   CDD; cd00472; Ribosomal_L24e_L24; 1.
DR   Gene3D; 2.30.170.20; Ribosomal protein L24e; 1.
DR   InterPro; IPR038630; L24e/L24_sf.
DR   InterPro; IPR000988; Ribosomal_eL24-rel.
DR   InterPro; IPR023442; Ribosomal_eL24_CS.
DR   InterPro; IPR011017; TRASH_dom.
DR   PANTHER; PTHR10792; 60S RIBOSOMAL PROTEIN L24; 1.
DR   PANTHER; PTHR10792:SF8; RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED; 1.
DR   Pfam; PF01246; Ribosomal_L24e; 1.
DR   SMART; SM00746; TRASH; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   PROSITE; PS01073; RIBOSOMAL_L24E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..164
FT                   /note="Probable ribosome biogenesis protein RLP24"
FT                   /id="PRO_0000136901"
FT   CONFLICT        43
FT                   /note="K -> E (in Ref. 1; BJ418184)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   164 AA;  19691 MW;  48AF01C17AB68637 CRC64;
     MRIEKCYFCS GPVYPGHGVM FVRNDCKQFR FCRSKCHKNF KLKRNPRKTR WTKAFRKLNG
     KEMTVDKTLE FEKKRNRPVK YDRELINNTI IAMARVQKIK ERREKTFYKN RMEGVKGMQK
     KQKLKEINQN LSLIRGPSAL NKLQERIKNN AEKIEQLTTT KMQS
//