ID RM31_SCHPO Reviewed; 115 AA.
AC Q9UR27;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=Large ribosomal subunit protein mL60 {ECO:0000305};
DE AltName: Full=54S ribosomal protein L31, mitochondrial;
DE AltName: Full=Negative regulator of cdc42 protein nrf20;
DE Flags: Precursor;
GN Name=mrpl31; Synonyms=nrf20; ORFNames=SPCC16A11.11;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=10628977; DOI=10.1093/genetics/154.1.155;
RA Murray J.M., Johnson D.I.;
RT "Isolation and characterization of Nrf1p, a novel negative regulator of the
RT Cdc42p GTPase in Schizosaccharomyces pombe.";
RL Genetics 154:155-165(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Component of the mitochondrial ribosome (mitoribosome), a
CC dedicated translation machinery responsible for the synthesis of
CC mitochondrial genome-encoded proteins, including at least some of the
CC essential transmembrane subunits of the mitochondrial respiratory
CC chain. The mitoribosomes are attached to the mitochondrial inner
CC membrane and translation products are cotranslationally integrated into
CC the membrane. {ECO:0000250|UniProtKB:P14063}.
CC -!- SUBUNIT: Component of the mitochondrial large ribosomal subunit (mt-
CC LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S)
CC and a large (54S) subunit. The 37S small subunit contains a 15S
CC ribosomal RNA (15S mt-rRNA) and at least 32 different proteins. The 54S
CC large subunit contains a 21S rRNA (21S mt-rRNA) and at least 45
CC different proteins. {ECO:0000250|UniProtKB:P14063}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL60 family. {ECO:0000305}.
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DR EMBL; AF087833; AAD53228.1; -; mRNA.
DR EMBL; CU329672; CAB53083.1; -; Genomic_DNA.
DR PIR; T41084; T41084.
DR RefSeq; NP_587998.1; NM_001022989.2.
DR AlphaFoldDB; Q9UR27; -.
DR SMR; Q9UR27; -.
DR STRING; 284812.Q9UR27; -.
DR iPTMnet; Q9UR27; -.
DR MaxQB; Q9UR27; -.
DR PaxDb; 4896-SPCC16A11-11-1; -.
DR EnsemblFungi; SPCC16A11.11.1; SPCC16A11.11.1:pep; SPCC16A11.11.
DR GeneID; 2538813; -.
DR KEGG; spo:SPCC16A11.11; -.
DR PomBase; SPCC16A11.11; mrpl31.
DR VEuPathDB; FungiDB:SPCC16A11.11; -.
DR eggNOG; ENOG502S81F; Eukaryota.
DR HOGENOM; CLU_141719_0_0_1; -.
DR InParanoid; Q9UR27; -.
DR OMA; HLVPKWT; -.
DR PhylomeDB; Q9UR27; -.
DR PRO; PR:Q9UR27; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0032543; P:mitochondrial translation; ISS:PomBase.
DR InterPro; IPR016340; Ribosomal_mL60.
DR PANTHER; PTHR28271; 54S RIBOSOMAL PROTEIN L31, MITOCHONDRIAL; 1.
DR PANTHER; PTHR28271:SF1; 54S RIBOSOMAL PROTEIN L31, MITOCHONDRIAL; 1.
DR Pfam; PF09784; L31; 1.
DR PIRSF; PIRSF002216; MRPL31_prd; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..23
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 24..115
FT /note="Large ribosomal subunit protein mL60"
FT /id="PRO_0000374039"
FT REGION 88..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 115 AA; 13355 MW; 46F53FB558B6A5F9 CRC64;
MLGAFNSTLA RFGGLVHKVP WRLSQRRKYR HRQRLRAVDE VVDVLRTALQ EKNQSCKRIE
SFVANHQPES QMSPKDKYTM FTRKTQGAGL QGFRKGVHKS PKWTRSTNRV NPTGF
//
