ID   RM48_BOVIN              Reviewed;         212 AA.
AC   Q2YDI5;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   24-JAN-2024, entry version 98.
DE   RecName: Full=Large ribosomal subunit protein mL48 {ECO:0000305};
DE   AltName: Full=39S ribosomal protein L48, mitochondrial;
DE            Short=L48mt;
DE            Short=MRP-L48;
DE   Flags: Precursor;
GN   Name=MRPL48;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=11551941; DOI=10.1074/jbc.m106510200;
RA   Koc E.C., Burkhart W., Blackburn K., Moyer M.B., Schlatzer D.M.,
RA   Moseley A., Spremulli L.L.;
RT   "The large subunit of the mammalian mitochondrial ribosome. Analysis of the
RT   complement of ribosomal proteins present.";
RL   J. Biol. Chem. 276:43958-43969(2001).
RN   [3]
RP   INTERACTION WITH OXA1L, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=20601428; DOI=10.1074/jbc.m110.148262;
RA   Haque M.E., Elmore K.B., Tripathy A., Koc H., Koc E.C., Spremulli L.L.;
RT   "Properties of the C-terminal tail of human mitochondrial inner membrane
RT   protein Oxa1L and its interactions with mammalian mitochondrial
RT   ribosomes.";
RL   J. Biol. Chem. 285:28353-28362(2010).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins (By
CC       similarity). Interacts with OXA1L (PubMed:20601428).
CC       {ECO:0000250|UniProtKB:Q96GC5, ECO:0000269|PubMed:20601428}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11551941}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL48 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC110207; AAI10208.1; -; mRNA.
DR   RefSeq; NP_001040028.1; NM_001046563.2.
DR   AlphaFoldDB; Q2YDI5; -.
DR   SMR; Q2YDI5; -.
DR   STRING; 9913.ENSBTAP00000042506; -.
DR   PaxDb; 9913-ENSBTAP00000042506; -.
DR   Ensembl; ENSBTAT00000045090.2; ENSBTAP00000042506.1; ENSBTAG00000008347.5.
DR   GeneID; 615873; -.
DR   KEGG; bta:615873; -.
DR   CTD; 51642; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008347; -.
DR   VGNC; VGNC:31643; MRPL48.
DR   eggNOG; KOG4060; Eukaryota.
DR   GeneTree; ENSGT00390000012955; -.
DR   HOGENOM; CLU_095928_0_0_1; -.
DR   InParanoid; Q2YDI5; -.
DR   OMA; MKQHTEA; -.
DR   TreeFam; TF315130; -.
DR   Reactome; R-BTA-5389840; Mitochondrial translation elongation.
DR   Reactome; R-BTA-5419276; Mitochondrial translation termination.
DR   Proteomes; UP000009136; Chromosome 15.
DR   Bgee; ENSBTAG00000008347; Expressed in oocyte and 105 other cell types or tissues.
DR   GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005761; C:mitochondrial ribosome; ISS:UniProtKB.
DR   Gene3D; 3.30.70.600; Ribosomal protein S10 domain; 1.
DR   InterPro; IPR027487; Ribosomal_mL48.
DR   InterPro; IPR027486; Ribosomal_uS10_dom.
DR   InterPro; IPR036838; Ribosomal_uS10_dom_sf.
DR   PANTHER; PTHR13473:SF0; 39S RIBOSOMAL PROTEIN L48, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13473; MITOCHONDRIAL RIBOSOMAL PROTEIN L48; 1.
DR   Pfam; PF00338; Ribosomal_S10; 1.
DR   SMART; SM01403; Ribosomal_S10; 1.
DR   SUPFAM; SSF54999; Ribosomal protein S10; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..212
FT                   /note="Large ribosomal subunit protein mL48"
FT                   /id="PRO_0000261656"
FT   MOD_RES         199
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8JZS9"
SQ   SEQUENCE   212 AA;  24022 MW;  61308D6503C2738C CRC64;
     MNGALGKVLC LKNDTIFKQA FSLLRFRTSG ENPVYSAGGI LLTTSRHYRS KPTHGIGRYK
     HLVKPEEPKK KKGKVEIRAI NVGTDYEYGT LNIHLIAYDM ALTESYAQYV HNLCNHLSIK
     VEESYAMPTK TMEVLQLQDQ GNKMLLDSVL TTHERVVQIS GLNATFAEIF LEIIQSNLPE
     GVKLSVREHT EEDFKGRFKA RPELEELLAK LN
//