ID RNK_ECO57 Reviewed; 136 AA.
AC P0AFW6; P40679;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=Regulator of nucleoside diphosphate kinase {ECO:0000255|HAMAP-Rule:MF_00954};
GN Name=rnk {ECO:0000255|HAMAP-Rule:MF_00954};
GN OrderedLocusNames=Z0754, ECs0649;
OS Escherichia coli O157:H7.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: May act as an anti-Gre factor. {ECO:0000255|HAMAP-
CC Rule:MF_00954}.
CC -!- SUBUNIT: Interacts with the RNA polymerase. {ECO:0000255|HAMAP-
CC Rule:MF_00954}.
CC -!- SIMILARITY: Belongs to the Rnk family. {ECO:0000255|HAMAP-
CC Rule:MF_00954}.
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DR EMBL; AE005174; AAG54945.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB34072.1; -; Genomic_DNA.
DR PIR; A90710; A90710.
DR PIR; E85560; E85560.
DR RefSeq; NP_308676.1; NC_002695.1.
DR RefSeq; WP_000089731.1; NZ_VOAI01000012.1.
DR AlphaFoldDB; P0AFW6; -.
DR SMR; P0AFW6; -.
DR STRING; 155864.Z0754; -.
DR GeneID; 75205028; -.
DR GeneID; 917008; -.
DR KEGG; ece:Z0754; -.
DR KEGG; ecs:ECs_0649; -.
DR PATRIC; fig|386585.9.peg.760; -.
DR eggNOG; COG0782; Bacteria.
DR HOGENOM; CLU_120358_1_1_6; -.
DR OMA; WTLVYPD; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR Gene3D; 1.10.286.20; -; 1.
DR Gene3D; 3.10.50.30; Transcription elongation factor, GreA/GreB, C-terminal domain; 1.
DR HAMAP; MF_00954; Rnk; 1.
DR InterPro; IPR036953; GreA/GreB_C_sf.
DR InterPro; IPR028625; Rnk.
DR InterPro; IPR029462; Rnk_N.
DR InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR PANTHER; PTHR30437:SF5; REGULATOR OF NUCLEOSIDE DIPHOSPHATE KINASE; 1.
DR PANTHER; PTHR30437; TRANSCRIPTION ELONGATION FACTOR GREA; 1.
DR Pfam; PF01272; GreA_GreB; 1.
DR Pfam; PF14760; Rnk_N; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..136
FT /note="Regulator of nucleoside diphosphate kinase"
FT /id="PRO_0000097388"
SQ SEQUENCE 136 AA; 14927 MW; 7043926623BA5E1E CRC64;
MSRPTIIIND LDAERIDILL EQPAYAGLPI ADALNAELDR AQMCSPEEMP HDVVTMNSRV
KFRNLSDGEV RVRTLVYPAK MTDSNTQLSV MAPVGAALLG LRVGDSIHWE LPGGVATHLE
VLELEYQPEA AGDYLL
//
