ID RPN9_SCHPO Reviewed; 381 AA.
AC Q9US13;
DT 15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 24-JAN-2024, entry version 134.
DE RecName: Full=Probable 26S proteasome regulatory subunit rpn9;
GN Name=rpn9; ORFNames=SPAC607.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Acts as a regulatory subunit of the 26S proteasome which is
CC involved in the ATP-dependent degradation of ubiquitinated proteins.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the proteasome subunit S11 family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB63792.1; -; Genomic_DNA.
DR PIR; T50225; T50225.
DR RefSeq; NP_593594.1; NM_001019025.2.
DR AlphaFoldDB; Q9US13; -.
DR SMR; Q9US13; -.
DR BioGRID; 279546; 13.
DR STRING; 284812.Q9US13; -.
DR MaxQB; Q9US13; -.
DR PaxDb; 4896-SPAC607-05-1; -.
DR EnsemblFungi; SPAC607.05.1; SPAC607.05.1:pep; SPAC607.05.
DR GeneID; 2543114; -.
DR KEGG; spo:SPAC607.05; -.
DR PomBase; SPAC607.05; rpn9.
DR VEuPathDB; FungiDB:SPAC607.05; -.
DR eggNOG; KOG2908; Eukaryota.
DR HOGENOM; CLU_042989_0_0_1; -.
DR InParanoid; Q9US13; -.
DR OMA; TWVQPRI; -.
DR PhylomeDB; Q9US13; -.
DR Reactome; R-SPO-1236978; Cross-presentation of soluble exogenous antigens (endosomes).
DR Reactome; R-SPO-350562; Regulation of ornithine decarboxylase (ODC).
DR Reactome; R-SPO-5689603; UCH proteinases.
DR Reactome; R-SPO-5689880; Ub-specific processing proteases.
DR Reactome; R-SPO-6798695; Neutrophil degranulation.
DR PRO; PR:Q9US13; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IDA:PomBase.
DR GO; GO:0005198; F:structural molecule activity; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IC:PomBase.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR035298; PSMD13.
DR InterPro; IPR040798; Rpn9_C.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10539; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR PANTHER; PTHR10539:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF18261; Rpn9_C; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome; Reference proteome.
FT CHAIN 1..381
FT /note="Probable 26S proteasome regulatory subunit rpn9"
FT /id="PRO_0000173869"
FT DOMAIN 177..343
FT /note="PCI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ SEQUENCE 381 AA; 43457 MW; 994D3916EDB6B1B0 CRC64;
MDTEMSVNMS DFLHDQATRA PESLQQSYIL MEDLYERKLW KQLTDALIVF FDTPETVPLR
LPLYTNFVNS FRPNINQLKA VYMGLKAFES CSNDEALRNL NQIVNELDEE KYKDAYVYSI
VAIARIKLIS GKLDEARELL VKASKIIDHI DYVESLIHSS YYSVSADYYK AKADYAQYYR
HCLLYLSCID LDKCSHTELV ERAVDLSVAA ILGDIYNFGE LLLHPVFELL VGTQHEWLHD
LVIAMNVGDL PLFERLMGQI NKMPLLQSSV ALLGQKIRLM ALIELVFQLP PNQRTLTFDT
IARATRIPSN EVELLIMRAL SVGLITGVID EVTQIVTISS VQSRILNHSQ IASMESRLRE
WNQNIKNLSN VVEISGKGVF V
//
