ID RSE1_CANAL Reviewed; 1219 AA.
AC Q5A7S5; A0A1D8PJ07;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-MAY-2023, entry version 84.
DE RecName: Full=Pre-mRNA-splicing factor RSE1;
GN Name=RSE1; Synonyms=SAP130; OrderedLocusNames=CAALFM_C300660WA;
GN ORFNames=CaO19.12846, CaO19.5391;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle control.
CC {ECO:0000250}.
CC -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RSE1 family. {ECO:0000305}.
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DR EMBL; CP017625; AOW28116.1; -; Genomic_DNA.
DR RefSeq; XP_717766.1; XM_712673.1.
DR AlphaFoldDB; Q5A7S5; -.
DR SMR; Q5A7S5; -.
DR STRING; 237561.Q5A7S5; -.
DR EnsemblFungi; C3_00660W_A-T; C3_00660W_A-T-p1; C3_00660W_A.
DR GeneID; 3640538; -.
DR KEGG; cal:CAALFM_C300660WA; -.
DR CGD; CAL0000182953; orf19.12846.
DR VEuPathDB; FungiDB:C3_00660W_A; -.
DR eggNOG; KOG1898; Eukaryota.
DR HOGENOM; CLU_003246_0_1_1; -.
DR InParanoid; Q5A7S5; -.
DR OMA; PRATGHW; -.
DR OrthoDB; 101343at2759; -.
DR PRO; PR:Q5A7S5; -.
DR Proteomes; UP000000559; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR PANTHER; PTHR10644:SF1; SPLICING FACTOR 3B SUBUNIT 3; 1.
DR Pfam; PF03178; CPSF_A; 1.
DR Pfam; PF10433; MMS1_N; 1.
PE 3: Inferred from homology;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT CHAIN 1..1219
FT /note="Pre-mRNA-splicing factor RSE1"
FT /id="PRO_0000218627"
SQ SEQUENCE 1219 AA; 136352 MW; C5E5CC30495E1C46 CRC64;
MMMRDGNISG PKKKKFTTKC RPFSFYKNRH IIMLINDESV YLYNLTLKPP SYYISSIVGQ
FYKQDNSTKN AQQLVLVSST TLQLFEINEE AGKLELQSSQ NLLGIINSIE KICLSEVDGV
VITSDSGNLS ILQYDNKTKK FISKIQEPMT KNGWGRNYVG ENLAIDPENR CILVAAMEKN
KLFYKIESNS SGSKELSSPL EAHSKQVLCL KIVALNTDHN NPLFGALELT PEKKCIINYY
ELDQGLNHVV KKKPNSSNSD PLPNDVNYLI PLPGHIGGMV VCGTNWCFYD KLDGPRIYLP
LPRRNGQTQD SIIVNHVTHV LKKKKFFILL QNALGDLFKL TVDYDFDKEI IKNISITYFD
TIPPALSLNI FKNGFLFANV LNNDKLLYQF EKLGDDLTEG ELVINSSDYE SLNSVRESVT
SFKLKGLDNL ALIDVLETLS PITDSKIIDS KLVTLSSHSY VKSITHGVPT TTLVESPLPI
TPTDIFTTKL SLESANDEYL VISSSLSSKT LVLSIGEVVE DVEDSEFVLD QPTIAVQQVG
IASVVQIYSN GIKHVRTVNG NKKTTDWFPP AGITITHATT NNQQVLIALS NLSVVYFEID
ATDDQLIEYQ DRLEIATTIT AMAIQENISE KSPFAIIGCS DETIQVVSLQ EHNCLEIKSL
QALSANSSSL KMLKSSGKET HVHIGMENGV YARIKIDTIN GNLSNSRVKY IGSKPVSLSV
IKFSNEIEGI LAISSAPWIS YLYRDSFKIT PLLEIDITNG SSFISEDIGG EGIVGIKDNN
LIIFSVGKED SVFDPSQDLT IATTKLRYTP RKMITNGNRL FISESEYNVQ GPFKCNINGD
VKENVDEDYY EAFGYEWKQN SWASCIQVVD SKSNQVIQSL QLDGNESIVS MSAVSFNKTS
TPSVPASHLV VGVCTNQTIL PNSYDKSYLY TFKIGKKHLQ LVHKTELDHI PQVLENFQDK
LLVASGNHIR LYDIGQKQLL KKSTTIIDFS TNINKIIPQT NRIIICDSHK SSIVFAKFDE
SQNQFVPFAD DVMKRQITSI MNLDIDTLIG GDKFGNIFVT RIDEDISKQA DDDWTILKTQ
DGILNSCPYK LQNLIEFHIG DIITSFNLGC LNLAGTESVI YTGLQGTIGL LIPLVSKSEV
ELLFNLQLYM QQSQNNLVGK DHLKLRSYYN PIKNVIDGDL LERFLEFDIS LKIEISRKLN
KSVNDIEKKL IDLRNRSAF
//
