ID RUSD1_DANRE Reviewed; 293 AA.
AC Q08C69;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=RNA pseudouridylate synthase domain-containing protein 1;
GN Name=rpusd1; ORFNames=zgc:153465;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC {ECO:0000305}.
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DR EMBL; BC124362; AAI24363.1; -; mRNA.
DR RefSeq; NP_001070221.1; NM_001076753.1.
DR AlphaFoldDB; Q08C69; -.
DR SMR; Q08C69; -.
DR STRING; 7955.ENSDARP00000113540; -.
DR PaxDb; 7955-ENSDARP00000113540; -.
DR GeneID; 767786; -.
DR KEGG; dre:767786; -.
DR AGR; ZFIN:ZDB-GENE-060929-444; -.
DR CTD; 113000; -.
DR ZFIN; ZDB-GENE-060929-444; rpusd1.
DR eggNOG; KOG1919; Eukaryota.
DR InParanoid; Q08C69; -.
DR OrthoDB; 5479603at2759; -.
DR PhylomeDB; Q08C69; -.
DR PRO; PR:Q08C69; -.
DR Proteomes; UP000000437; Chromosome 3.
DR GO; GO:0009982; F:pseudouridine synthase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IBA:GO_Central.
DR CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR PANTHER; PTHR21600:SF100; RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..293
FT /note="RNA pseudouridylate synthase domain-containing
FT protein 1"
FT /id="PRO_0000300818"
FT ACT_SITE 67
FT /evidence="ECO:0000250"
SQ SEQUENCE 293 AA; 33340 MW; 4A84CC1E562E2867 CRC64;
MEPASLENLS VLYQSTNYIV VNKHWDIRID SKMWYEKQTV QSQLKHHFPE LADPGTYYGF
RFCHQLDFST SGALCVALNK AAAGQAYRCF KDRRVTKAYL ALVRGTVTEE NLSLDFAIGK
NTTEGKTHMM CTEGTEGCEN PKPCQTEVTV LEYGTYDGDQ VTKVLLQPLT GRTHQLRVHC
SAIGHPIVGD YTYSLRTDNS PYRMMLHAYF LHIPLHNEPI HVTAPDPFVP SLDAKWAPLR
CVNILEDLLK NILTKLQAAM QEEAEPEPRT SSPVESEEQR AQCQQWLCEW SLE
//
