ID S0DJP2_GIBF5 Unreviewed; 454 AA.
AC S0DJP2;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=N-acetylgalactosaminide beta-1,3-galactosyltransferase {ECO:0000256|ARBA:ARBA00012557};
DE EC=2.4.1.122 {ECO:0000256|ARBA:ARBA00012557};
GN ORFNames=FFUJ_00891 {ECO:0000313|EMBL:CCT62550.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT62550.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-
CC galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-
CC galactosaminyl derivative + H(+) + UDP; Xref=Rhea:RHEA:15621,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28257, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:66914, ChEBI:CHEBI:133470; EC=2.4.1.122;
CC Evidence={ECO:0000256|ARBA:ARBA00000862};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T
CC subfamily. {ECO:0000256|ARBA:ARBA00006462}.
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DR EMBL; HF679023; CCT62550.1; -; Genomic_DNA.
DR AlphaFoldDB; S0DJP2; -.
DR STRING; 1279085.S0DJP2; -.
DR EnsemblFungi; CCT62550; CCT62550; FFUJ_00891.
DR VEuPathDB; FungiDB:FFUJ_00891; -.
DR HOGENOM; CLU_033556_0_0_1; -.
DR OrthoDB; 2664045at2759; -.
DR Proteomes; UP000016800; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR026050; C1GALT1/C1GALT1_chp1.
DR InterPro; IPR003378; Fringe-like_glycosylTrfase.
DR InterPro; IPR003609; Pan_app.
DR PANTHER; PTHR23033:SF47; APPLE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23033; BETA1,3-GALACTOSYLTRANSFERASE; 1.
DR Pfam; PF02434; Fringe; 1.
DR Pfam; PF00024; PAN_1; 1.
DR SUPFAM; SSF57414; Hairpin loop containing domain-like; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 187..304
FT /note="Fringe-like glycosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF02434"
FT DOMAIN 384..426
FT /note="Apple"
FT /evidence="ECO:0000259|Pfam:PF00024"
SQ SEQUENCE 454 AA; 51508 MW; D36EFC9696B9F489 CRC64;
MVVISRRTRR RLRSILILIL ISTFIIYSIL PHDSAIRLAF VFNISRFFNF LRGAATNRDA
WLWKSPRYAV DLKNEVGYLI KTGYGTRHRV PDQLAAFEAT GGFLGKEGES FLVVGDWTTV
NQTDAKLIGV TVHDAIKRVM ETKVRGKVDD YPRLVKYTSL QAKLQAGDEE EALKIGQSYG
WELDALKFIM GMEMIYHQLP GKKWYIILDD DTFLIRPSLE LLMGHVDYRK PRYIGNAVGD
YKARFGHGGS GILISGEAMR RLFEHPGIVQ EAYAESMTET WGDRLVATTL QKLGIYIEES
YNHHFNGEPP SITRIWGDRF CSPLLSFHGL RKPGEMRRVG ETLAKIDKPV LWHDVWQLFG
GSAMSALESR PTELTADHVG KPDEHTRSWG DVRSANACQK RCEQSGRRCL AWTYEMEIER
CHTSPWLLLG ADGATGKASG VNWPEVKPLL KGCR
//
