ID S0DPH0_GIBF5 Unreviewed; 875 AA.
AC S0DPH0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Probable KAP95 protein {ECO:0000313|EMBL:CCT64454.1};
GN ORFNames=FFUJ_04322 {ECO:0000313|EMBL:CCT64454.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT64454.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|EMBL:CCT64454.1, ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR EMBL; HF679024; CCT64454.1; -; Genomic_DNA.
DR AlphaFoldDB; S0DPH0; -.
DR STRING; 1279085.S0DPH0; -.
DR EnsemblFungi; CCT64454; CCT64454; FFUJ_04322.
DR VEuPathDB; FungiDB:FFUJ_04322; -.
DR HOGENOM; CLU_008296_1_0_1; -.
DR OrthoDB; 124901at2759; -.
DR Proteomes; UP000016800; Chromosome 2.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:1990023; C:mitotic spindle midzone; IEA:EnsemblFungi.
DR GO; GO:0042564; C:NLS-dependent protein nuclear import complex; IEA:EnsemblFungi.
DR GO; GO:0005635; C:nuclear envelope; IEA:EnsemblFungi.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0097718; F:disordered domain specific binding; IEA:EnsemblFungi.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:EnsemblFungi.
DR GO; GO:0061676; F:importin-alpha family protein binding; IEA:EnsemblFungi.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:EnsemblFungi.
DR GO; GO:0044877; F:protein-containing complex binding; IEA:EnsemblFungi.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006607; P:NLS-bearing protein import into nucleus; IEA:EnsemblFungi.
DR GO; GO:0051292; P:nuclear pore complex assembly; IEA:EnsemblFungi.
DR GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IEA:EnsemblFungi.
DR GO; GO:0006612; P:protein targeting to membrane; IEA:EnsemblFungi.
DR GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IEA:EnsemblFungi.
DR GO; GO:0060188; P:regulation of protein desumoylation; IEA:EnsemblFungi.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016800}.
FT DOMAIN 24..105
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 413..450
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 875 AA; 96063 MW; 8DB185ED70A676C5 CRC64;
MSSSEINQVL TNSLSPDANL RNAAEQQLTQ AAESNFPLYL ATLVQELAND SADGSIRAAA
GIALKNAFTT RDFARHQELQ AKWLQQTDDE TKNRVKELTL QTLNSSNTQA GTAAAQVISS
IAAIELPRGQ WNDLLPFLVK NVSEGADHQK QSSLTTIGYI CESQDAELRG ALVTHSNAIL
TAVVQGARKE ETNIEVRLAA ITALGDSLEF VGNNFKHEGE RNYIMQVVCE ATQADDSRIQ
QGAFGCLNRI MALYYENMRF YMEKALFGLT ILGMKSDDED VAKLAVEFWS TVCEEEISIE
DDNAQVESSD QMRPFYNFAR VAANEVVPVL LLLLTKQDED ATDDEYNLSR AAYQCLQLYA
QAVGATIITP VLQFVEGNLR HEDWHNRDAA VSAFGAIMEG PDEKVLDPIV KQALPILITM
MDDQSLHVKD STAYALGRIT EACSEAIDPQ AQLPTLIESL FKGLLSSAKM APSCCWALMN
LAERFAGDLG ASSNAITPHF NNAVSSLLDV TARTETETSV RTAAYEVLNV FVQNAASESL
QPVASLSDVI IKRLEETVPL QNQVVSVEDK ITLEEMQNSL CTVLQAIISR LDKEIIPQGD
RIMQILLQIL NSVGGKSSVP DAVFATISAL STAMEEDFVK YMDAFAPFLY NALGNQDEPS
LCSMAIGLVS DITRSLGERS QPYCDNFMNY LLNNLRSTTL ANQFKPAILQ CFGDIAGAIG
GHFETYLSVV AQVLEQATTV TASPEGPYEM YDYVVSLREG IMDAWGGIIG AMKVSEKTQA
LQQYVPLIFN ALSIIANDMN RSESLMRASM GVIGDLADAY PDGQLVDAFR QDWLTVMIKE
TKTNREFQPR TIETARWARE QVKRQLGGSQ AVMAN
//
