ID S0DS29_GIBF5 Unreviewed; 502 AA.
AC S0DS29;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Related to translation initiation factor eIF-2B subunit family protein {ECO:0000313|EMBL:CCT64192.1};
GN ORFNames=FFUJ_04611 {ECO:0000313|EMBL:CCT64192.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT64192.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|EMBL:CCT64192.1, ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR EMBL; HF679024; CCT64192.1; -; Genomic_DNA.
DR AlphaFoldDB; S0DS29; -.
DR STRING; 1279085.S0DS29; -.
DR EnsemblFungi; CCT64192; CCT64192; FFUJ_04611.
DR VEuPathDB; FungiDB:FFUJ_04611; -.
DR HOGENOM; CLU_021101_1_0_1; -.
DR OrthoDB; 1406448at2759; -.
DR Proteomes; UP000016800; Chromosome 2.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04664; Nudix_Hydrolase_7; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43475; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR43475:SF3; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G14290); 1.
DR Pfam; PF01008; IF-2B; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:CCT64192.1};
KW Protein biosynthesis {ECO:0000313|EMBL:CCT64192.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800}.
FT DOMAIN 5..152
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 502 AA; 55387 MW; B34707502B3E1EC5 CRC64;
MAPLKHKDVA TSFIFRFPAD GEAKKPQVAL FRRSGHVNTY QHKYAGISGS VDDTDADPIA
TAWRELAEET TLTHDSLRLF RKGKPFSFVD ESIGREWTVN PFGFLLKSES DGGRGEAGIK
IDWEHEGYEW FDPDAINDCD DFGGVPRILE SLRRVWFNVD LGQEAGNTLS RGLVALQEDH
ESGARQLATK ALDTYIDVMK KVDFTDQVQW WNNIRFAGWH LWKNGRESMG ASILNVVLLA
LDIVQNGIPP RGPLDKSSID NIIRALGDYA RDRQNTTSRT GAMFQTFIEQ HLSGGGPLKI
LTLSSSSTIT SAITHVMGNT SRPVEVHVLE SRPLFEGVKM AQSIASCANN SKARSRLIIH
TDASVGIAAK DIDIVLIGAD LIDKTAAVSN KIGSLPAVLT AKYVSLKAKI VVLSEKEKVL
PFAPPGQEKN DSCEVMQAWG DLSSAVREVP HSLVTVKNVY FEWVSPDLID HYITEDGVTG
RAGISNYAQE VEKKADQYFT NL
//
