ID S0DY97_GIBF5 Unreviewed; 1918 AA.
AC S0DY97;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
GN ORFNames=FFUJ_13455 {ECO:0000313|EMBL:CCT67506.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT67506.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- FUNCTION: Involved in the initiation of assembly of the COPII coat
CC required for the formation of transport vesicles from the endoplasmic
CC reticulum (ER) and the selection of cargo molecules. Also involved in
CC autophagy. {ECO:0000256|ARBA:ARBA00024687,
CC ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
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DR EMBL; HF679026; CCT67506.1; -; Genomic_DNA.
DR STRING; 1279085.S0DY97; -.
DR EnsemblFungi; CCT67506; CCT67506; FFUJ_13455.
DR VEuPathDB; FungiDB:FFUJ_13455; -.
DR HOGENOM; CLU_001147_0_0_1; -.
DR OrthoDB; 1361743at2759; -.
DR Proteomes; UP000016800; Chromosome 4.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR InterPro; IPR024468; Sec16_N.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR PANTHER; PTHR13402:SF6; SECRETORY 16, ISOFORM I; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
DR Pfam; PF12935; Sec16_N; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|RuleBase:RU364101};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101}; Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 237..459
FT /note="Sec16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12935"
FT DOMAIN 969..1087
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 1147..1450
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1448..1497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1512..1577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1589..1918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..356
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..473
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..585
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..672
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..909
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..931
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1470..1497
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1605..1649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1672..1727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1794..1839
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1863..1891
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1918 AA; 204310 MW; 685F2A177D518F7E CRC64;
MASESPKATD LATMPNHPDP TSSTQAPAHA TSSTTPDAVV QADVPTSPDV SSQQDQKSSE
QDGAANAWPS HEDDGHDSND WLASDDAVPN QTQEETASNE PELDVASQPK APVSQHSSSM
SFARTVSHEI SFGDEEEGEW NLSRTDTDPF KFMPPTDRTN SFPPVPPAHT NSEVEDQQPL
ASNQALDVLE EIEKEADAEE ELYQREETTD GLEAPRRGHS SSISIGGDLK SPEGQDSDER
YEEGMPLIPP PEEERHKVPS EQPNHTLSDS FDDKAEEGDD FFSQVQGSEQ PSDEKPTPAL
ERKSTMQVLD SMNAGAISNK SALEGTPEEE EEEEEEKEEE EEEEEEEEEE EEDDDDSKKA
AQPAPTPASS NPAAAAPDSS PAKKEDLASK WEQAFADDED DDFLLEENAG DDKQVDPAAF
FGSDDEGFLE DEEPASAPAP APAPAPASRQ PSGSNPYMPQ APAPHPAPSP YAPSIQVPAA
AGSQISAYNT PAPVVTPFGT SPQYGQPLPA RPDMSKAQSF ADKSKGGYHS PYDLPTDLVT
NLVKPRKRAS MQQLSQANQL HAPVQPPPRS ASVGMPAPPT RLTPPSSSHG LPSHQQSTAP
PKPTTPGAQH KENFFEELPL TSRPRPSSRT SQRALSPARN APPMAHVPHI PSPLAPAAPN
HMVPPPFPAT TVTPGEPHSD STGQPALVPG AGLVAPERVS PYAALTTSAN HMPPPASTST
SRYSPAPGTS HTAPPAPASS RYSPAPPVPK SHGSYGAVAT AGPGPVLPHQ PRTSSPLTHS
ESAHFEPRMS RVSSLPPTRE VDEEDEQQTP TRSASATHAI PHYDSRYNPA SPPKSTQTPP
PPSYAGQLTL SPPKQSGPYV PHAPPTAQAG FVPPPRAQTQ SPSASFGHKQ AQRSSDSARR
PSSAHSHSYP SPVGGKPAPS PYAPVAPTAP MAPAPGVSTV RTRGQSITMN MVAPTDGREN
DELQRWKGVP IISWGVGGTV VTSFPKSVPR YGMNQAVPMI VRTPGEVKVQ SVKDIEPLHE
HVAKFPGPLR GKSKKKETIG WLSAGIELLE KDLPDVSFHS QLSLEAKRAV ERLLLWKIML
IFIENDGILE SNPAVEAAVR DVLSPGENTS SASDDALFPA AASFDTGVPS VTSMQADGVD
VSSMDQIRHH LLRGDRDKAV WALVDKRLWG HAMLISHTVE GDLYKRVAQE FVRKEVNYPG
HANESMAALY KILSGNLEDC VDELVPVHAR AGLQLVSTGG GSGPTKDTLD GLDKWRETLS
LVLSNRSTDD IQGLNALGNL LSSYGRAEAA HICFIFGRHA SIFGGLDDPN ANFVLIGADH
RQQSDQFAKE TEALQLSEVY EYGLSLAGGA LAAAGTPHLA AYKLEHAMTL AEYGHRDKAM
QYCDAILTAM SSQTKRSPYH HHVLETAVED FMLRLKQAPK EESGSWISKP SMNKVSDSMW
NRFNKFVAGD DNEENNGGTG EAGPFNRPSG EFSRSPSVSN FDIYGQQSPS FGMTPAQPSA
SIAASKYAPN ASTPAASANL YSPTSQYTPG RSSTEYAPNS YEPSYPGAAS TDRGEGYTPS
VPPSEPTSAG LSGPAGLAPA AQITQGYSPA GYQPYGMPAS TPMGNDETPA DSSSQGFQPL
SYGYEPPQVS SNPPEQAGEH NTGESGNGGY EPPSFQPYGY EPPSYEPQST AEGDDEQPKP
KKKSFMDDDD DDFPSMKPAE KSKADKDREN DEMFRKAAEE DAKRAAAQQS SKKGWGFGGW
FGGSKKAPLE QTSSGDSSPG KPIRAKLGEA SSFVYDPELK RWVNKKPGAE NTPAKTATPP
PPRAGPRSVS GTPPPPTATP PPPLVTSNSA PPPLMPPKVR AGTPELSKQV STESLGLAPP
AMVRSVSNTS NASAPPSRPT TSMSNASSID DLLSVAPRKA SDKKKPRKGG RYVDVMAK
//
