ID S0E3D5_GIBF5 Unreviewed; 981 AA.
AC S0E3D5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Related to OSBP-related protein 7 {ECO:0000313|EMBL:CCT69354.1};
GN ORFNames=FFUJ_07373 {ECO:0000313|EMBL:CCT69354.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT69354.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|ARBA:ARBA00008842}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HF679027; CCT69354.1; -; Genomic_DNA.
DR AlphaFoldDB; S0E3D5; -.
DR STRING; 1279085.S0E3D5; -.
DR EnsemblFungi; CCT69354; CCT69354; FFUJ_07373.
DR VEuPathDB; FungiDB:FFUJ_07373; -.
DR HOGENOM; CLU_007105_4_0_1; -.
DR OrthoDB; 960at2759; -.
DR Proteomes; UP000016800; Chromosome 5.
DR GO; GO:0032541; C:cortical endoplasmic reticulum; IEA:EnsemblFungi.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblFungi.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0120015; F:sterol transfer activity; IEA:EnsemblFungi.
DR GO; GO:0006897; P:endocytosis; IEA:EnsemblFungi.
DR GO; GO:0035621; P:ER to Golgi ceramide transport; IEA:EnsemblFungi.
DR GO; GO:0006887; P:exocytosis; IEA:EnsemblFungi.
DR GO; GO:0001403; P:invasive growth in response to glucose limitation; IEA:EnsemblFungi.
DR GO; GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IEA:EnsemblFungi.
DR GO; GO:0030011; P:maintenance of cell polarity; IEA:EnsemblFungi.
DR GO; GO:0034727; P:piecemeal microautophagy of the nucleus; IEA:EnsemblFungi.
DR GO; GO:0007124; P:pseudohyphal growth; IEA:EnsemblFungi.
DR CDD; cd13289; PH_Osh3p_yeast; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF216; OXYSTEROL-BINDING PROTEIN HOMOLOG 3; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..142
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT DOMAIN 210..304
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 49..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 903..930
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 49..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..548
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 981 AA; 107879 MW; 7FDDA38F80BDA81C CRC64;
MAGIEQLESY IVRWVKVDEG NTLSWSVQPH KKSINFGIVK HPGSGATTFA SSTAEDLNNG
TEESGGTSDG KSARFSKKDI NAQELLKSKG FIPIKWIGKC EADKVSIGTY EVNHDQSGMY
GLVFDNTFSK QTSKTATFVV MTYPTGAPPQ TSSHLPNLQA PKAGASQTSL GRHSSPKLDG
LASASLDSLH SHNAVANANS VSGRSEVGSG NYHVGVLHKR RRKKGQGYAR RFFSLDYSTC
TLSYYYNPKS SALRGAIPLS LAAIAADERR REISIDSGAE VWHLRAPNDK EFQDWAHALE
KASRVARGLE TLDLPKNDHL KINTRQLQPI HQSSPQEDRE WEQVESLVSR VVGTRDALRR
LTREVTAQAK PPPVTSPQYL SPGAATSAID ENDTYFTPPP EQRRSFWRRK SNTPAISPAT
LGAPTAMAVP APGGVTTTIS ANVPNHSRRQ SKGLVREENS LQDHCQSLLM DLDSVVSEFT
TLINNSKRRR MPVPLSAGGV SRKSIDTVST ADEFFDAEDA NSAVLKIDGS EDEASRSEEA
EDEEEDSFRD NSSVSSIGEN DTANLDDASH LFPTKPKSLT PLPIEQVVVR RSTIPPAAAA
APSLIAFFRK NVGKDFSTIS MPVTSNEPSS MCQKVAEQLE YAQLLNQAAK QSSPTDRLLF
VAAFAVSQFS SGRAKERAIR KPFTPLLGET FELVRSEKEV PGGFRLLVEK VQHRPLLLAM
QADSANWSFS QSPAPGQKFW GKSAEITTDG RVRIVLRLSN GSEERYSWNI ATMFLRNVVM
GEKYVEPVGT MHVVNDSTCH KAAVEFKSKG MWGGRIEDVS VEIFNPEGVN TGSGLVGTWT
NSLKTTGKGG GQEIWRVGPL VENAAQTFGL TTFAASLNEI TEIEKGKLPP TDCRLRPDQR
AYEQGAIDDA EDLKQKLEEA QRGRRRELEE RGETYKPRWF VKVENAPEGE EVWKLKTGKD
SYWEERAKGS WQGVEDLFKL T
//
