ID S0E8P3_GIBF5 Unreviewed; 1089 AA.
AC S0E8P3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Probable nitrite reductase {ECO:0000313|EMBL:CCT70152.1};
GN ORFNames=FFUJ_06099 {ECO:0000313|EMBL:CCT70152.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT70152.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- COFACTOR:
CC Name=siroheme; Xref=ChEBI:CHEBI:60052;
CC Evidence={ECO:0000256|ARBA:ARBA00001929};
CC -!- PATHWAY: Nitrogen metabolism; nitrate reduction (assimilation).
CC {ECO:0000256|ARBA:ARBA00005096}.
CC -!- SIMILARITY: Belongs to the nitrite and sulfite reductase 4Fe-4S domain
CC family. {ECO:0000256|ARBA:ARBA00010429}.
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DR EMBL; HF679028; CCT70152.1; -; Genomic_DNA.
DR AlphaFoldDB; S0E8P3; -.
DR SMR; S0E8P3; -.
DR STRING; 1279085.S0E8P3; -.
DR EnsemblFungi; CCT70152; CCT70152; FFUJ_06099.
DR VEuPathDB; FungiDB:FFUJ_06099; -.
DR HOGENOM; CLU_003291_0_0_1; -.
DR OrthoDB; 275583at2759; -.
DR UniPathway; UPA00653; -.
DR Proteomes; UP000016800; Chromosome 6.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008942; F:nitrite reductase [NAD(P)H] activity; IEA:InterPro.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-UniPathway.
DR CDD; cd03529; Rieske_NirD; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 1.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR InterPro; IPR012748; Rieske-like_NirD.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR NCBIfam; TIGR02378; nirD_assim_sml; 1.
DR PANTHER; PTHR43809; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR PANTHER; PTHR43809:SF1; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF01077; NIR_SIR; 1.
DR Pfam; PF03460; NIR_SIR_ferr; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF00355; Rieske; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00397; SIROHAEM.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 1.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 1.
DR PROSITE; PS00365; NIR_SIR; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800}.
FT DOMAIN 901..1011
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
SQ SEQUENCE 1089 AA; 118871 MW; 6EE3E4169DA93B1B CRC64;
MTATAQKRVV VVGLGMVGIA FIEKLLKYDA KSKEYAITVV GEEPYLAYNR VGLTTFFEHR
NVEELYMNPA EWYTEAGSSL NCHINTKATH INTEDKFIEC ANGESYPYDI LVLATGSDAI
LPRMLKGWDA NGVFVYRTIE DLNKLIKFSH DKKGTNGAVV GGGLLGLEAA KAMLDLETFN
RVDVIEKAQW VLTRQVDETG GKMVADQVSQ LGVNLNLGKG VSSMKTDENN NLTGVIFDDG
SEISCSTLCF AVGVKPRDDL ARSANLEVGQ RGGIVVNDDL RTSMPDIYAI GECASWRGMA
YGLIAPGVAM AEVVAFNLTQ AKLHSPQTFK TPDMSTKLKL LGVNVASFGD CFADRDGPVT
LPPKYARTLV NGDAKEPKSV QALTYKDPFS NVYKKYIFTK DGKYLLGGMM IGDVCDYVKL
LPMVKAQKEL EISPSELILG AKKDGGEDTD DLDDDAQVCS CHNVTKGDIV KVVKDGTCKD
VASLKKCTKA GTGCGGCVPL ITTIFNKTMA SMGQEVTNYV CSHFNHSRAD LFNIIMVKRL
NNMGEVMREA GNDKEALGCE LCKPVVASIM ASLWNRHVMD KTTHGLQETN DRFLGNIQRD
GTYSVVPRVS GGEITPDKLV VIGEVAQKYN LYTKITGGQR IDLFGAQKQD LLDIWGQLVA
GGMESGHAYA KSLRTVKSCV GSTWCRFGLS DSVGMAVRLE ERYKSIRAPH KIKGGVSGCV
RECAEAQGKD FGLIATEKGW NIFVGGNGGA NPRHAELLAK DVPPTDVVTI LDRYLMFYMR
TADKLQRTAR WIENLPGGIK YLQEVILEDK LGINASLEAQ MEELVDSFFD EWAEAIKSPA
IAAKFKQFAN TNDTTRNMEL EDDRGQKRPA FWPADAAATD NFSGLKDKWS MTSWEPIIES
SYFDGADELP NGISATIKRG DTQLAIWRIK GVYYATQQMC PHKRAFILSD GLIGQEPSKA
VTNGDKDGAS PWVSCPHHKR NFDLGNGACK TDESLSIATF PTEARADGML YLKLPPVEEL
DAALGTKKWM VKKGEAGEAP LAKLDSKIKF VGLRGKKPYV KPTGGAKMTT KPLDLMMAAN
GCGGGAPEW
//
