ID S0E9N5_GIBF5 Unreviewed; 1079 AA.
AC S0E9N5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Probable nuclear export factor CRM1 {ECO:0000313|EMBL:CCT71606.1};
GN ORFNames=FFUJ_08304 {ECO:0000313|EMBL:CCT71606.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT71606.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; HF679029; CCT71606.1; -; Genomic_DNA.
DR AlphaFoldDB; S0E9N5; -.
DR STRING; 1279085.S0E9N5; -.
DR EnsemblFungi; CCT71606; CCT71606; FFUJ_08304.
DR VEuPathDB; FungiDB:FFUJ_08304; -.
DR HOGENOM; CLU_011906_0_0_1; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000016800; Chromosome 7.
DR GO; GO:0000776; C:kinetochore; IEA:EnsemblFungi.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0005816; C:spindle pole body; IEA:EnsemblFungi.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:EnsemblFungi.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:EnsemblFungi.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030619; F:U1 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030620; F:U2 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030621; F:U4 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030623; F:U5 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0017070; F:U6 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0006611; P:protein export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0034501; P:protein localization to kinetochore; IEA:EnsemblFungi.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 26..92
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REGION 1049..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1073
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1079 AA; 123682 MW; D993B7D01E620464 CRC64;
MAASIEELDV LVRSFYEGRG EQQKAAQAAL NQFKEDPDAW LMVDKILSDA QYPQTKYLGL
QVLDNVILTR WKVLPREQCQ GIRNFIVQFI IQCSSTEESL RQQKTLLNKL NLVLVSVLKQ
EWPHNWPTFI NEIISSCHSN LSICENNMII LRLLSEEVFD YSAEQMTSTK TRNLKQTMCA
EFSQIFNLCQ EVLNTATQPS LIKATLETLL RFCNWIPLGY IFETPLIETL RTRFLSTPEF
RNVTMQCLTE IGGLQTGGPG QPNSYDEQLV KMFTETLTTI ANIIPVSLDL KSTYPSSNSR
DQEFIQNLAL FLCNFFGMHL NLIEKLPNRD FLIHGHYYLI RISQIDDREI FKICLDYWLK
LVQELYEEMQ QLPMTDLNPL MAVGAGMSGS GAPNPTMLNN YPLRKHKYNE VLSNLRVVMI
EKMVRPEEVL IVENDEGEIV REFVKESDTV QLYKTIRECL VYLTHLDVVD TENIMTEKLA
RQVDGSEWSW HNCNVLCWAI GSISLAMNEE TEKRFLVTVI KDLLGLTEMK RGKDNKAVVA
SNIMYIVGQY PRFLKAHWKF LKTVVNKLFE FMHESHEGVQ DMACDTFIKI ARQCRRHFVA
LQPSEQEPFI EEIVRNMGKI TCDLTPQQVH TFYEACGYMV AAQGNKHQQE RLLADLMAIP
NAAWDEIIKQ ATVNPTILQD AETIKVIGNI MKTNVSACSS VGSYFYPQIG RIYHDMLQMY
NATSTLISEA VARDGELATK MPKVRGLRTI KKEILKLIEV YVDKAEDLQA VRAQMVPPLL
ESVLVDYNRN VPGARDAEVL KACSTIITKL SALMEDQVPT IMQNVFECTL EMINKDFSEF
PEHRVEFFNL LRAINLHCFP ALLKLDNNQF KFVIDSCSWA FKHDNRDVEA AGLNMALELI
NNIAEKTDVQ TANAFFQRFF ITILQDVFFV VTDNDHKAGF KTQSMLLMKL FYYINPADGS
QPKIQGPIYS PDQAAAGTDN REFVANFVAN LLQNAFRNLQ ANQITSFVEG LFTLNTQYDK
FRLNLRDFLV SLKEFAGDNA ELFIVEKEQQ EQDAKTADME RRQKVGGLLK PSELEDEEL
//
