ID S0EEY2_GIBF5 Unreviewed; 324 AA.
AC S0EEY2;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Related to monophenol monooxygenase (Tyrosinase) {ECO:0000313|EMBL:CCT73319.1};
GN ORFNames=FFUJ_09995 {ECO:0000313|EMBL:CCT73319.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT73319.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR EMBL; HF679031; CCT73319.1; -; Genomic_DNA.
DR AlphaFoldDB; S0EEY2; -.
DR STRING; 1279085.S0EEY2; -.
DR EnsemblFungi; CCT73319; CCT73319; FFUJ_09995.
DR VEuPathDB; FungiDB:FFUJ_09995; -.
DR HOGENOM; CLU_035914_1_2_1; -.
DR OrthoDB; 4070889at2759; -.
DR Proteomes; UP000016800; Chromosome 9.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Monooxygenase {ECO:0000313|EMBL:CCT73319.1};
KW Oxidoreductase {ECO:0000313|EMBL:CCT73319.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..324
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004485553"
FT DOMAIN 67..268
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|Pfam:PF00264"
SQ SEQUENCE 324 AA; 36053 MW; EF2744E630CB4082 CRC64;
MKLTSILALT GAITPAIAAP AKSDKTCSNS AKRIEWRELD ASDQQGYIDA VLCLKTKPSR
MGLNSSLYDD FPHLHFQLNS WIHGGSPFLP WHRYFGVVHE RALRDCGYEG PYTYWDWTKD
TEGLRLSPVM ASKNGFGGNG DAEKTEISAS GSTLKCVSDG PFAKLRPEYL ETEPRELTDG
GHCLHRNLPE VDEPDAFATM AKVFGPEGVE EVQASGNWSH YAQTLEGGPH GSIHACLGGE
MNPTTSPNEP LFFLHHAQID RLWWLWQKEN STRLTEYNGL YKNINQTEQH EVSLKDILVM
GGIDEDLTVG DVMDTTNGPL CYTY
//
