ID S0EGA3_GIBF5 Unreviewed; 411 AA.
AC S0EGA3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Related to O-methyltransferase B {ECO:0000313|EMBL:CCT73670.1};
GN ORFNames=FFUJ_09518 {ECO:0000313|EMBL:CCT73670.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT73670.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Cation-independent O-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00038277}.
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DR EMBL; HF679031; CCT73670.1; -; Genomic_DNA.
DR AlphaFoldDB; S0EGA3; -.
DR STRING; 1279085.S0EGA3; -.
DR EnsemblFungi; CCT73670; CCT73670; FFUJ_09518.
DR VEuPathDB; FungiDB:FFUJ_09518; -.
DR HOGENOM; CLU_005533_5_2_1; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000016800; Chromosome 9.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF20; O-METHYLTRANSFERASE ASQN; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CCT73670.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:CCT73670.1}.
FT DOMAIN 183..386
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 316
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 411 AA; 45648 MW; E5064AECA58E78F2 CRC64;
MALPSKQEIN DLVSSLNDAA KAYSDATDLN GYMSRVQILE KARSLTNALI TPDQKPNYHG
LNIAELVAIR TFMKLKVLNA IPATGSISLQ DLSQATGVQD SLLERMGRVL VASGFLDQTE
PDGGEYKHTK FSLAYILDEP APGHLFLAMY DEWFKHMHNF DDYLVSKGRY EEPQDPLYNP
YTAYWKQEGT PVWSIMMQNP ERFQTFQTGM AGIDVAIPVT GHFDFSTLKN EFPDTDNATI
ELVDVGGGEG TVLNKILEAH PELSPRNCVL QERPEVIQLA KSKKTLPDDV QLVEHDFMTE
QPVKGAKAYF MRMILHDYAD AVGTQILTRL AEAMKPYSRV LVCEMVLAPR VGEADFASAV
LDQAVMTMGG KERTEAGFQK MFDASGLELV KTWRMPGVPG GCVEARLKGQ A
//
