ID S0EKN7_GIBF5 Unreviewed; 345 AA.
AC S0EKN7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Related to NADPH-dependent aldehyde reductase {ECO:0000313|EMBL:CCT75401.1};
GN ORFNames=FFUJ_11421 {ECO:0000313|EMBL:CCT75401.1};
OS Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS and foot rot disease fungus) (Fusarium fujikuroi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=1279085 {ECO:0000313|EMBL:CCT75401.1, ECO:0000313|Proteomes:UP000016800};
RN [1] {ECO:0000313|Proteomes:UP000016800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831
RC {ECO:0000313|Proteomes:UP000016800};
RX PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA Wiemann P., Sieber C.M., von Bargen K.W., Studt L., Niehaus E.M.,
RA Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA Proctor R.H., Munsterkotter M., Freitag M., Humpf H.U., Guldener U.,
RA Tudzynski B.;
RT "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT novel metabolites.";
RL PLoS Pathog. 9:E1003475-E1003475(2013).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; HF679033; CCT75401.1; -; Genomic_DNA.
DR AlphaFoldDB; S0EKN7; -.
DR STRING; 1279085.S0EKN7; -.
DR EnsemblFungi; CCT75401; CCT75401; FFUJ_11421.
DR VEuPathDB; FungiDB:FFUJ_11421; -.
DR HOGENOM; CLU_007383_9_2_1; -.
DR OrthoDB; 552946at2759; -.
DR Proteomes; UP000016800; Chromosome 11.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF562; ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360); 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016800}.
FT DOMAIN 14..261
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 345 AA; 38304 MW; 113630AD88D11602 CRC64;
MSSPSTAIPT GSWVLVTGAT GFVASHVTRQ LLQRGYKVRG TVRDQGKAQW LIDDHFKSYA
DSGSYELVTV PDISAAGAFD DAVKGVSAVA HIASVLDFDP NPNNVVPQTV AGVTSVLESA
SKEPSVTRFV FTSSIVAAVF PTPDSDGVVD RNSWNEFAIK AAWAPPPYEP SRAMLVYAAS
KVAAEQALWK YIDENKPHFV ANAICPSGIL GEPLHERHAT SYGNWIYSLF IEKRGMIDTF
QTAFFVDVQD VALLHVAALL DPELKDARLQ TWGHKAHWNN FLPILRELRP QRKFIPDYPE
TFYLKLSTDQ SESVALLKKW AGQEDWKPIR QIITEAINNP YWKTE
//
