ID S0EU46_CHTCT Unreviewed; 425 AA.
AC S0EU46;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN ORFNames=CCALI_01310 {ECO:0000313|EMBL:CCW35128.1};
OS Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49).
OC Bacteria; Armatimonadota; Chthonomonadetes; Chthonomonadales;
OC Chthonomonadaceae; Chthonomonas.
OX NCBI_TaxID=1303518 {ECO:0000313|EMBL:CCW35128.1, ECO:0000313|Proteomes:UP000014227};
RN [1] {ECO:0000313|Proteomes:UP000014227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23976 / ICMP 18418 / T49
RC {ECO:0000313|Proteomes:UP000014227};
RA Lee K.C.Y., Morgan X.C., Dunfield P.F., Tamas I., Houghton K.M.,
RA Vyssotski M., Ryan J.L.J., Lagutin K., McDonald I.R., Stott M.B.;
RT "Genome sequence of Chthonomonas calidirosea, the first sequenced genome
RT from the Armatimonadetes phylum (formally candidate division OP10).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369}.
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DR EMBL; HF951689; CCW35128.1; -; Genomic_DNA.
DR RefSeq; WP_016482669.1; NC_021487.1.
DR AlphaFoldDB; S0EU46; -.
DR STRING; 454171.CP488_02785; -.
DR KEGG; ccz:CCALI_01310; -.
DR PATRIC; fig|1303518.3.peg.1336; -.
DR eggNOG; COG0372; Bacteria.
DR HOGENOM; CLU_025068_2_1_0; -.
DR InParanoid; S0EU46; -.
DR OrthoDB; 9800864at2; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000014227; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR011278; 2-MeCitrate/Citrate_synth_II.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01800; cit_synth_II; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:CCW35128.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014227};
KW Transferase {ECO:0000256|PIRNR:PIRNR001369, ECO:0000313|EMBL:CCW35128.1}.
FT ACT_SITE 310
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 361
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 425 AA; 48126 MW; 6CF4E61E12CC4F22 CRC64;
MVQKQLRPVA LYLASSQRFS APTRRRKEKD FLFGKKKIFI KQEFSEEPFH AKRILQPWTR
GHVAGLTAIS KIDAERNRLS YRGYDIHDLV DHCSFDEVAY LLIYGDLPNQ SQLDAFCKTV
GAHRGVPSEV ISLLRTLPPA ASQMDRVKAA VAALALFDPQ REERTAETYR AVAVRLYAQL
PTIIVNSYRL SQGQEPATPR ADLNHNANFF WMLTGHEPSD LIGRAFNVSQ ILYAEHGYNA
STFAARVTVS TLSDIYSGVV SAIGTLKGPL HGGANEASMQ MLLEIGSPER AAEWVREALA
RKQRIMGFGH REYKHGDERA RIAKQYVIEL VNSKGATHWL EMADIIEREM MQAKGLYPNV
DFPIGLLYYL MDIPIPLYTP IFMMSRITGW CAHIIEQLEN NRLIRPESEY IGPSERPVLP
LSQRP
//
