ID S0EVZ4_CHTCT Unreviewed; 763 AA.
AC S0EVZ4;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU364053};
DE EC=5.6.2.4 {ECO:0000256|RuleBase:RU364053};
GN ORFNames=CCALI_02195 {ECO:0000313|EMBL:CCW36002.1};
OS Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49).
OC Bacteria; Armatimonadota; Chthonomonadetes; Chthonomonadales;
OC Chthonomonadaceae; Chthonomonas.
OX NCBI_TaxID=1303518 {ECO:0000313|EMBL:CCW36002.1, ECO:0000313|Proteomes:UP000014227};
RN [1] {ECO:0000313|Proteomes:UP000014227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23976 / ICMP 18418 / T49
RC {ECO:0000313|Proteomes:UP000014227};
RA Lee K.C.Y., Morgan X.C., Dunfield P.F., Tamas I., Houghton K.M.,
RA Vyssotski M., Ryan J.L.J., Lagutin K., McDonald I.R., Stott M.B.;
RT "Genome sequence of Chthonomonas calidirosea, the first sequenced genome
RT from the Armatimonadetes phylum (formally candidate division OP10).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618,
CC ECO:0000256|RuleBase:RU364053};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922, ECO:0000256|RuleBase:RU364053}.
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DR EMBL; HF951689; CCW36002.1; -; Genomic_DNA.
DR AlphaFoldDB; S0EVZ4; -.
DR STRING; 454171.CP488_01898; -.
DR KEGG; ccz:CCALI_02195; -.
DR PATRIC; fig|1303518.3.peg.2280; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_004585_5_2_0; -.
DR InParanoid; S0EVZ4; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000014227; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR005751; ATP-dep_DNA_helicase_PcrA.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR01073; pcrA; 1.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF21196; PcrA_UvrD_tudor; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA-binding {ECO:0000256|RuleBase:RU364053};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000014227}.
FT DOMAIN 31..311
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 312..587
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 52..59
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 763 AA; 86736 MW; 4A96A08380057E10 CRC64;
MDETVKPAEP PFSQPDANSE AQQATQERLL QGLNPVQREA VLHAEGPLLL FAGAGSGKTR
VLTHRIAYLT AVRRVPPQRI LAVTFTNKAA KEMKERLDHL VGGKVGKKLW VGTFHAICAR
LLREFAPEAG LSHEFVVYDD SDQVSLVKEC LRAINLDESK FPPRTMLDRI SRAKESLIPP
EEWDKHYSGY LEEIAGRIYR LYQQKLRQNN ALDFDDLLTE TVRLLQNNTG VLQHLQDRWR
YLLVDEYQDV NLVQYLLLKL LAQKHRNLCV VGDDDQSIYS WRGADVNLIL RFEKDYPDAK
VLKLEQNYRS TRRILDAAYA VVSNNKGRKE KRLWTENPEG PPLTKYEAAT ERLEAEWVVN
TITMQVQSGK RKWSDFAVLY RTNAQSRVLE EMLRAWAVPY RIVGGLRFYD RKEIKDALAY
LRVVHNPNDS VSLKRIINVP ARGIGNTTLA KLEAETLLAG SSLWEVLGNE QVLTEFNTRT
RKNLSEFREL ILGLRALRDT LSVHDLLKTT LERSGYLQAL HEENSLEAQG RLENLAELLQ
AAVEFEATTE SPTLAAFLES TALVSDIDSL EEGVPAVTLM TLHAAKGLEF PVVFLTGLEE
GVFPHMRSLE KSEQLEEERR LCYVGITRAK EELYLSCARQ RSQFLGTAYN PPSRFLKEIP
ETLFAFNKKP CSRSSLSTFD PDREAGGMPS RLWQEGPRPP SEAVRQQGEA FYRAGQRVRH
PQFGEGVVLR VSGEGDDAII EIAFPNVGPR RLMLSYAKLE RVR
//
