ID S0GKA6_9BACT Unreviewed; 619 AA.
AC S0GKA6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Beta-glucuronidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=C803_05465 {ECO:0000313|EMBL:EOS12960.1};
OS Parabacteroides goldsteinii dnLKV18.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=1235789 {ECO:0000313|EMBL:EOS12960.1, ECO:0000313|Proteomes:UP000014140};
RN [1] {ECO:0000313|EMBL:EOS12960.1, ECO:0000313|Proteomes:UP000014140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=dnLKV18 {ECO:0000313|Proteomes:UP000014140};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Kuhn K., Stappenbeck T., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Parabacteroides goldsteinii dnLKV18.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS12960.1}.
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DR EMBL; ASSQ01000025; EOS12960.1; -; Genomic_DNA.
DR RefSeq; WP_010800243.1; NZ_KE159524.1.
DR AlphaFoldDB; S0GKA6; -.
DR PATRIC; fig|1235789.3.peg.5470; -.
DR HOGENOM; CLU_009935_2_1_10; -.
DR Proteomes; UP000014140; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..619
FT /note="Beta-glucuronidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004497811"
FT DOMAIN 91..194
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 241..297
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 336..606
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 619 AA; 71746 MW; 7E70294DF79B1083 CRC64;
MKRILNISTF LLFCCITALF AVPRAEYPRP QFERASWVNL NGEWTCSFDF GGSGMERGFY
KSKGFDKKIT VPFCPESKLS GIGYTDFINH FWYQRSISIP QEWDGKNILL NFGAVYYKSE
VYIDGVLANR HFGGTSSFSV DITDFVKPGQ THSLVVYVES DVRGAKQPAG KQNLQYESYA
CNYTRTTGIW QTVWMEAVHS EGVQSVQILT DIDQQQIVVR PRFYKELGGK FQVILKDNGK
VVASQTVTAC SLSSVVLPVR KMKTWSPENP FLYDLEYKVL DKNGIVVDEV KAYAGMRKVH
IEGNKVFLNN QPYYQRLVLD QGFYPDGIWT APSDTALKRD IILAMEAGFN GARLHQKVFE
ERFYYWADKL GYLTWGEASS WGMDCNDVET ARNFITEWCE IVQRDRNHPS LLIWTPTNEQ
FWPDRVQYPR MMNDLYNLTK MIDPTRPFHG TSGGVHIATD IWTIHNYEQN PAELKKQLYN
DGKLFVTPKW EIQLMPKNIG FNGLKYTDQY RFLEYKKDMP YLVDEFGGIK WNPVQQMESA
QNISWGYGEP PRSLEEFYAR LKGQVDVVLS LSNDIWGYCY TQLTDVEQEQ NGIYYYDRTP
KFDMKRIHAI FSKTPESKN
//
