ID S0GKE6_9BACT Unreviewed; 546 AA.
AC S0GKE6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=C803_01117 {ECO:0000313|EMBL:EOS18954.1};
OS Parabacteroides goldsteinii dnLKV18.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=1235789 {ECO:0000313|EMBL:EOS18954.1, ECO:0000313|Proteomes:UP000014140};
RN [1] {ECO:0000313|EMBL:EOS18954.1, ECO:0000313|Proteomes:UP000014140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=dnLKV18 {ECO:0000313|Proteomes:UP000014140};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Kuhn K., Stappenbeck T., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Parabacteroides goldsteinii dnLKV18.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS18954.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ASSQ01000005; EOS18954.1; -; Genomic_DNA.
DR RefSeq; WP_010803237.1; NZ_KE159513.1.
DR AlphaFoldDB; S0GKE6; -.
DR PATRIC; fig|1235789.3.peg.1123; -.
DR HOGENOM; CLU_007082_5_1_10; -.
DR Proteomes; UP000014140; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..546
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004497876"
FT DOMAIN 28..156
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 160..510
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 327
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 546 AA; 62027 MW; DB5BBC1070FE5C3A CRC64;
MIFNTKKLKI TSLLLLAATL SFGQSNTSAL LPLPNRIEQM TGKKNFVLTP RTTIKTNLPK
QAFCLFELQR ILGERTGQVA DIGAPSTSGN SVIEIELDPS IKGKEHYMLD ISEKKLSIKG
SSHAALFYGL KTLDQILLGD VCNTANNQIA PIRIDDEPRY GYRALMLDPA RHFLPVEDVK
FYINQMAKYK YNVLQLHLTD DQGWRVEIKK HPRLTEIGAF RNPKTGSNGP DNGFYTQEQL
KDLIKYAADR NVEIIPELDI PGHTVAVLAT YPELGCTHTD TIQKIMGQTV DLMLCANNDK
VYTVYDDIIK EIADIFPSSK IHLGGDEAVI EKNWTKCTHC QDLMKQLGYT KESQLMNYFF
DKILASVRKY GKEPMLWCEL DNVRMPANEY LFDYPKDATL ITWRAGLTPK CIELTAKHGN
PLIMAPGEYT YLDYPQLKGD LPEFKNWGMP VTTLETCYRF DPGYGLPAAQ QAHILGITGT
LWGEAMQDIN RVTYMTYPRG LALAEAGWTQ MEHRSWDSFK ERMYPNLMNL MKHGVFVRVP
FEIVPR
//
