ID S0ISD0_9FIRM Unreviewed; 713 AA.
AC S0ISD0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=PAS domain S-box protein {ECO:0000313|EMBL:EOT23484.1};
GN ORFNames=C805_03145 {ECO:0000313|EMBL:EOT23484.1};
OS Eubacterium sp. 14-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1235790 {ECO:0000313|EMBL:EOT23484.1, ECO:0000313|Proteomes:UP000014176};
RN [1] {ECO:0000313|EMBL:EOT23484.1, ECO:0000313|Proteomes:UP000014176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=14-2 {ECO:0000313|EMBL:EOT23484.1,
RC ECO:0000313|Proteomes:UP000014176};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Eubacterium bacterium 14-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT23484.1}.
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DR EMBL; ASSS01000012; EOT23484.1; -; Genomic_DNA.
DR RefSeq; WP_016216167.1; NZ_KE159568.1.
DR AlphaFoldDB; S0ISD0; -.
DR STRING; 1235790.C805_03145; -.
DR PATRIC; fig|1235790.3.peg.3400; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_8_1_9; -.
DR OrthoDB; 9803970at2; -.
DR Proteomes; UP000014176; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.30.1340.10; HPr-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000032; HPr-like.
DR InterPro; IPR035895; HPr-like_sf.
DR InterPro; IPR030828; HTH_TypR.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071:SF119; SIGMA-54 INTERACTING PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF18024; HTH_50; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00381; PTS-HPr; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF55594; HPr-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS51350; PTS_HPR_DOM; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014176};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..97
FT /note="HPr"
FT /evidence="ECO:0000259|PROSITE:PS51350"
FT DOMAIN 123..161
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 233..274
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 370..599
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 713 AA; 80519 MW; 908AF9ADB3CAA8CC CRC64;
MREDRTEAVV KIRSEKGLHV RIAAMLVQKA ERLRRKYHVN FHIRRKGFHD VPLTSLLLVT
SMKIKKNEEI ILITQGEQVE EAAAEMKEFL EGDFLENDLN LNQAELSQVD TLLQEHVITA
ENIYSSIASG LVVTDKQETV IIYNREAEKL LGIPEREALG RRAEEVFGGS KMLRAIRDKE
PMTVYTQTIG TSTMVGNTRP ILENGEIKGT ITTLEDVSQL VRISWEFEEV KELKEKYYQI
LEAVQDGICV FDQKGIVTYV NGAWQDITGE QVQEGADILA FDDGGSAARV LEKGQKIMGT
ICQKKNGKNL VLNVVPIIVN QQILGGISVV KSLSEVQELV ERIHHLSAKT EYLEEELNRR
NKLNPAFNRI VGISSKLYDA MQLAAKTADN NFNVLIRGES GTGKELIAEA IHYSSGRASH
DFIRVNCAAI PENLLESEMF GHVKGAYTGA IKTKIGKFEL AHKGTIFLDE IGELDKSMQA
KMLRVIQKKE FQRVGDDRTI QVDARIIAAT NRNLEELVEK GEFREDLYYR LNVIPIWLPP
LRERREDIPV LAEHFLNKIA ADLNREPKYL TPEAMEAILR YSWPGNIREL ENVMERVNIL
ADRAQVGRKD LPHYISENYT GGSYEKHGFA YGNSGAENAA AGEGRISPQN SLSLPGDMGW
EAQELYPWEY YEKEIIRRAL ETYGSFNGAG KALGLTHKTV ASKARKYQLE TKR
//
