ID S0J3X9_9FIRM Unreviewed; 253 AA.
AC S0J3X9;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Cell division protein ZapA {ECO:0000256|ARBA:ARBA00015195};
DE AltName: Full=Z ring-associated protein ZapA {ECO:0000256|ARBA:ARBA00033158};
GN ORFNames=C805_01627 {ECO:0000313|EMBL:EOT27519.1};
OS Eubacterium sp. 14-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1235790 {ECO:0000313|EMBL:EOT27519.1, ECO:0000313|Proteomes:UP000014176};
RN [1] {ECO:0000313|EMBL:EOT27519.1, ECO:0000313|Proteomes:UP000014176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=14-2 {ECO:0000313|EMBL:EOT27519.1,
RC ECO:0000313|Proteomes:UP000014176};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Eubacterium bacterium 14-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activator of cell division through the inhibition of FtsZ
CC GTPase activity, therefore promoting FtsZ assembly into bundles of
CC protofilaments necessary for the formation of the division Z ring. It
CC is recruited early at mid-cell but it is not essential for cell
CC division. {ECO:0000256|ARBA:ARBA00024910}.
CC -!- SUBUNIT: Homodimer. Interacts with FtsZ.
CC {ECO:0000256|ARBA:ARBA00026068}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT27519.1}.
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DR EMBL; ASSS01000005; EOT27519.1; -; Genomic_DNA.
DR AlphaFoldDB; S0J3X9; -.
DR STRING; 1235790.C805_01627; -.
DR PATRIC; fig|1235790.3.peg.1736; -.
DR eggNOG; COG3027; Bacteria.
DR HOGENOM; CLU_1097296_0_0_9; -.
DR OrthoDB; 1826286at2; -.
DR Proteomes; UP000014176; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.790; -; 1.
DR InterPro; IPR007838; Cell_div_ZapA-like.
DR InterPro; IPR036192; Cell_div_ZapA-like_sf.
DR PANTHER; PTHR34981; CELL DIVISION PROTEIN ZAPA; 1.
DR PANTHER; PTHR34981:SF1; CELL DIVISION PROTEIN ZAPA; 1.
DR Pfam; PF05164; ZapA; 1.
DR SUPFAM; SSF102829; Cell division protein ZapA-like; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000014176};
KW Septation {ECO:0000256|ARBA:ARBA00023210}.
FT REGION 140..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 67..129
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 150..164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 253 AA; 28201 MW; C56773D5E353F747 CRC64;
MSAKTSADVL IGGKIYTLSG YESEDYLQRV ANYINNKINE FDEMEQFRRF PGETKSTLVQ
LNIADDYFKA REQAEKLDRD VREKEKELYE LKHELISLRI KAESSEKATT ELEKENRRLL
LNKAKLESAL EDALLGKVKG QVVPEPQADT GERGKQKKTS GEGEPGGQKK TSGEGEAGRQ
KKTSGEGEAG RQKKTSGEGE AEGQKKTPGT GESGGQRKGP EPVHRDRKKH RGEEKLPDGP
EDKEETENEN HSV
//