ID S0KEE3_9ENTE Unreviewed; 389 AA.
AC S0KEE3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:EOT43082.1};
GN ORFNames=OMK_00417 {ECO:0000313|EMBL:EOT43082.1};
OS Enterococcus dispar ATCC 51266.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1139219 {ECO:0000313|EMBL:EOT43082.1, ECO:0000313|Proteomes:UP000014127};
RN [1] {ECO:0000313|EMBL:EOT43082.1, ECO:0000313|Proteomes:UP000014127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51266 {ECO:0000313|EMBL:EOT43082.1,
RC ECO:0000313|Proteomes:UP000014127};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Russ C., Gilmore M., Surin D., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus dispar ATCC_51266 (Illumina only
RT assembly).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT43082.1}.
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DR EMBL; AHYR01000003; EOT43082.1; -; Genomic_DNA.
DR RefSeq; WP_016171641.1; NZ_KE136354.1.
DR AlphaFoldDB; S0KEE3; -.
DR STRING; 44009.RV01_GL000620; -.
DR PATRIC; fig|1139219.3.peg.404; -.
DR eggNOG; COG1092; Bacteria.
DR HOGENOM; CLU_014042_1_2_9; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000014127; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43042:SF3; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K; 1.
DR PANTHER; PTHR43042; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EOT43082.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014127};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EOT43082.1}.
FT DOMAIN 3..64
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 161..348
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 389 AA; 43951 MW; 40E742D27F656FEE CRC64;
MKIQMNKFGV KKMRQHYPLV QVDDIVSDLK TTSGWVDFVD QNGNFLAKGY LGKQNKGIGW
VLSWQDELID QAFYARSFAK AKGMRQALFN DAATNTFRLF NGEGDGIGGI TIEWYDHYAI
FSWYNHTLYE EKEKIIAAFK EIYPEVLGAY EKIRFISELP ESTHLYGQIA PEPLIVKENF
VNFATYLNEG LMTGIFLDQR SVRGLLVDGL AAGKTLLNMF SYTGAFSVAA AMGGASSTTS
VDLAKRSLPK TREQFEVNGL DVSAQKIHVM DVFNYFSYAL KKDLKYDVIV LDPPSFARNK
KQVFKVKNNY GQLIAESLPI LSDDGIIIAS ANTANVTLEK FQQMIEKEFI TAKVDYRLLA
TKRLPVDFQV NPAFPEGNYL KVLIYQVTQ
//
