ID S0KLD1_9ENTE Unreviewed; 776 AA.
AC S0KLD1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=ABC transporter ATP-binding protein/permease {ECO:0000313|EMBL:EOT83408.1};
GN ORFNames=I573_01958 {ECO:0000313|EMBL:EOT83408.1};
OS Enterococcus sulfureus ATCC 49903.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1140003 {ECO:0000313|EMBL:EOT83408.1, ECO:0000313|Proteomes:UP000015961};
RN [1] {ECO:0000313|EMBL:EOT83408.1, ECO:0000313|Proteomes:UP000015961}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49903 {ECO:0000313|EMBL:EOT83408.1,
RC ECO:0000313|Proteomes:UP000015961};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Russ C., Gilmore M., Surin D., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus sulfureus ATCC_49903 (PacBio/Illumina
RT hybrid assembly).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Macrolide
CC exporter (TC 3.A.1.122) family. {ECO:0000256|ARBA:ARBA00038388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT83408.1}.
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DR EMBL; ASWO01000006; EOT83408.1; -; Genomic_DNA.
DR RefSeq; WP_016186526.1; NZ_KE136397.1.
DR AlphaFoldDB; S0KLD1; -.
DR STRING; 1140003.OMY_02096; -.
DR PATRIC; fig|1140003.3.peg.2021; -.
DR eggNOG; COG0577; Bacteria.
DR eggNOG; COG1136; Bacteria.
DR OrthoDB; 2079174at2; -.
DR Proteomes; UP000015961; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR017911; MacB-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42798:SF6; ABC TRANSPORTER, ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42798; LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF02687; FtsX; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EOT83408.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015961};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..668
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..240
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 776 AA; 85163 MW; 8CA8B6DFFF1EF153 CRC64;
MLNLKDIKKY YNVGGTETRA LDGVTVAFRK KEFVAILGPS GSGKTTMLNV IGGLDQYDSG
DLIINGQSTK HFKLTDWDAY RNNSIGFVFQ SYNLIGHQGI LDNVELGMTL SGIPKEERRK
RAQEALERVG LKDHLNKKPS QLSGGQMQRV AIARALANDP EILLCDEPTG ALDSETSVQI
MNLIQELSQE KLVIMVTHNP DLAREYADRI IEFSDGKILT DSNPYIEEKP DNDFELKRTR
MSFLTALRLS FNNIRTKKGR TFLTSFASSI GIIGIAIVLS LSNGFQKQID KTQSETLAQF
PVTISQITQD NTELFSNANT KKQEKAAKDQ VLAKTSEQDL AQHTNDLSTE YVDYIKKINP
DWSNNVSFSR STNLNLLRDV DGTIKQVQFS NAKAEGQNAA SFATSTGVGI SVFPDQLDPS
KDNFLKQNYQ VVDGQYPSNP NDLVLIVDEN GTTNVNALNN LGFDVKNGES ISYQDILGTT
IKLAFNNAYY TKLPTGNFIP NQDLTKVYDN SQNQTLKIVG ILKAKSSATM DLLAPGIAYS
DSLTQEVIKQ NKDSEIVKAQ DQSKTNVLTN ETLDETKKAA VLTYLGANAT PSSIYIYPNN
FKTKEKILTY LDDYNKGKDK ADQVLYTDLA GTMTKLTGGL MDAITYVLVA FAGISLVTSM
IMIGILTYTS VLERTKEIGV LKALGARKKD ITRVFDAETA ILGVASGVLG VAIAYAATFP
INQILENLTD LQNVAQLNPI HAVILIVIST ILTMLGGHLP ARMAAKKDAA IALRAE
//
