ID   S1QX01_9ENTE            Unreviewed;       233 AA.
AC   S1QX01;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Alpha-acetolactate decarboxylase {ECO:0000256|ARBA:ARBA00020164, ECO:0000256|PIRNR:PIRNR001332};
DE            EC=4.1.1.5 {ECO:0000256|ARBA:ARBA00013204, ECO:0000256|PIRNR:PIRNR001332};
GN   ORFNames=OMO_02259 {ECO:0000313|EMBL:ESK60597.1};
OS   Enterococcus cecorum DSM 20682 = ATCC 43198.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1121864 {ECO:0000313|EMBL:ESK60597.1, ECO:0000313|Proteomes:UP000017415};
RN   [1] {ECO:0000313|EMBL:ESK60597.1, ECO:0000313|Proteomes:UP000017415}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43198 {ECO:0000313|EMBL:ESK60597.1,
RC   ECO:0000313|Proteomes:UP000017415};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Russ C., Gilmore M., Surin D., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Enterococcus cecorum DSM 20682 (= ATCC 43198)
RT   (Illumina assembly).";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2S)-2-acetolactate + H(+) = (R)-acetoin + CO2;
CC         Xref=Rhea:RHEA:21580, ChEBI:CHEBI:15378, ChEBI:CHEBI:15686,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58476; EC=4.1.1.5;
CC         Evidence={ECO:0000256|ARBA:ARBA00001784,
CC         ECO:0000256|PIRNR:PIRNR001332};
CC   -!- PATHWAY: Polyol metabolism; (R,R)-butane-2,3-diol biosynthesis; (R,R)-
CC       butane-2,3-diol from pyruvate: step 2/3.
CC       {ECO:0000256|ARBA:ARBA00005170, ECO:0000256|PIRNR:PIRNR001332}.
CC   -!- SIMILARITY: Belongs to the alpha-acetolactate decarboxylase family.
CC       {ECO:0000256|ARBA:ARBA00007106, ECO:0000256|PIRNR:PIRNR001332}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESK60597.1}.
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DR   EMBL; AHYS01000011; ESK60597.1; -; Genomic_DNA.
DR   RefSeq; WP_016251503.1; NZ_KI535314.1.
DR   AlphaFoldDB; S1QX01; -.
DR   STRING; 44008.GCA_001318175_00116; -.
DR   GeneID; 60870962; -.
DR   PATRIC; fig|1121864.4.peg.1335; -.
DR   eggNOG; COG3527; Bacteria.
DR   HOGENOM; CLU_072561_0_0_9; -.
DR   OrthoDB; 8612680at2; -.
DR   UniPathway; UPA00626; UER00678.
DR   Proteomes; UP000017415; Unassembled WGS sequence.
DR   GO; GO:0047605; F:acetolactate decarboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0045151; P:acetoin biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd17299; acetolactate_decarboxylase; 1.
DR   InterPro; IPR005128; Acetolactate_a_deCO2ase.
DR   NCBIfam; TIGR01252; acetolac_decarb; 1.
DR   PANTHER; PTHR35524; ALPHA-ACETOLACTATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR35524:SF1; ALPHA-ACETOLACTATE DECARBOXYLASE; 1.
DR   Pfam; PF03306; AAL_decarboxy; 1.
DR   PIRSF; PIRSF001332; Acetolac_decarb; 1.
DR   SUPFAM; SSF117856; AF0104/ALDC/Ptd012-like; 1.
PE   3: Inferred from homology;
KW   Acetoin biosynthesis {ECO:0000256|ARBA:ARBA00023061,
KW   ECO:0000256|PIRNR:PIRNR001332};
KW   Decarboxylase {ECO:0000256|ARBA:ARBA00022793,
KW   ECO:0000256|PIRNR:PIRNR001332};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001332};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017415}.
SQ   SEQUENCE   233 AA;  25882 MW;  EF90C61299BCB9AD CRC64;
     MSENTLYQFG TLSSLLAGAM DGGKTINDLL KHGDFGIGTL DGSDGELMVI NGQAFHARQT
     GDVVKLSGNE TVPYAAVAYF EPKYEFPLIQ NENSKTIGKL IYDHLKSVNL FHAIQIKGTF
     KHMHVRVVPK QQKPYRPFSA VVQPEFEADN ISGTIVGFYT PELFHGVSVS GYHLHFLSDD
     GQFGGHIMDY ELAEGIITMQ ALTEFTQGFP STQNFLETEF DVHELIKEIE VSE
//