ID S1RHZ7_9ENTE Unreviewed; 200 AA.
AC S1RHZ7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=PglD N-terminal domain-containing protein {ECO:0000259|Pfam:PF17836};
GN ORFNames=OMO_02352 {ECO:0000313|EMBL:ESK60689.1};
OS Enterococcus cecorum DSM 20682 = ATCC 43198.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1121864 {ECO:0000313|EMBL:ESK60689.1, ECO:0000313|Proteomes:UP000017415};
RN [1] {ECO:0000313|EMBL:ESK60689.1, ECO:0000313|Proteomes:UP000017415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43198 {ECO:0000313|EMBL:ESK60689.1,
RC ECO:0000313|Proteomes:UP000017415};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Russ C., Gilmore M., Surin D., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus cecorum DSM 20682 (= ATCC 43198)
RT (Illumina assembly).";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK60689.1}.
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DR EMBL; AHYS01000011; ESK60689.1; -; Genomic_DNA.
DR RefSeq; WP_016251577.1; NZ_KI535314.1.
DR AlphaFoldDB; S1RHZ7; -.
DR GeneID; 60871053; -.
DR PATRIC; fig|1121864.4.peg.1429; -.
DR eggNOG; COG0110; Bacteria.
DR HOGENOM; CLU_081811_2_0_9; -.
DR OrthoDB; 9794407at2; -.
DR Proteomes; UP000017415; Unassembled WGS sequence.
DR CDD; cd03360; LbH_AT_putative; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF00132; Hexapep; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017415}.
FT DOMAIN 3..77
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT ACT_SITE 130
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT BINDING 32..33
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 66
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 139
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 160
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT SITE 131
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 200 AA; 21278 MW; F80B89115024C590 CRC64;
MNRLIIIGAG GHGKVIADVA IKCGYRNIKF LDDNIVGNCF GFPIIGKIKD LENYNDGSTN
FIIAIGNNKI RKTIAQKYKI DWCNLVHPTA VISTNVQLGV GTVIMANAVV NADAKIGNHC
IINSSAVVEH DNTIGDFVHI SPNVSIAGNV KIGELTHIGI GATLKNNIII EKNIIIGAGA
VVTKNILSEG RYVGIPAKKL
//
