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Database: UniProt
Entry: S2EAQ0_9ARCH
LinkDB: S2EAQ0_9ARCH
Original site: S2EAQ0_9ARCH 
ID   S2EAQ0_9ARCH            Unreviewed;       154 AA.
AC   S2EAQ0;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Iron dependent repressor, N-terminal DNA binding domain protein {ECO:0000313|EMBL:EPA06451.1};
GN   ORFNames=BG20_I0483 {ECO:0000313|EMBL:EPA06451.1};
OS   Candidatus Nitrosarchaeum limnium BG20.
OC   Archaea; Nitrososphaerota; Nitrososphaeria; Nitrosopumilales;
OC   Nitrosopumilaceae; Nitrosarchaeum.
OX   NCBI_TaxID=859192 {ECO:0000313|EMBL:EPA06451.1, ECO:0000313|Proteomes:UP000014065};
RN   [1] {ECO:0000313|EMBL:EPA06451.1, ECO:0000313|Proteomes:UP000014065}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BG20 {ECO:0000313|EMBL:EPA06451.1,
RC   ECO:0000313|Proteomes:UP000014065};
RX   PubMed=22461554; DOI=10.1128/JB.00007-12;
RA   Mosier A.C., Allen E.E., Kim M., Ferriera S., Francis C.A.;
RT   "Genome Sequence of "Candidatus Nitrosoarchaeum limnia" BG20, a Low-
RT   Salinity Ammonia-Oxidizing Archaeon from the San Francisco Bay Estuary.";
RL   J. Bacteriol. 194:2119-2120(2012).
CC   -!- SIMILARITY: Belongs to the DtxR/MntR family.
CC       {ECO:0000256|ARBA:ARBA00007871}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPA06451.1}.
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DR   EMBL; AHJG01000050; EPA06451.1; -; Genomic_DNA.
DR   RefSeq; WP_010190107.1; NZ_AHJG01000050.1.
DR   AlphaFoldDB; S2EAQ0; -.
DR   PATRIC; fig|859192.6.peg.401; -.
DR   OrthoDB; 24735at2157; -.
DR   Proteomes; UP000014065; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   Gene3D; 1.10.60.10; Iron dependent repressor, metal binding and dimerisation domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001367; Fe_dep_repressor.
DR   InterPro; IPR036421; Fe_dep_repressor_sf.
DR   InterPro; IPR022687; HTH_DTXR.
DR   InterPro; IPR022689; Iron_dep_repressor.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR   PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR   Pfam; PF02742; Fe_dep_repr_C; 1.
DR   Pfam; PF01325; Fe_dep_repress; 1.
DR   SMART; SM00529; HTH_DTXR; 1.
DR   SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50944; HTH_DTXR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014065};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          23..84
FT                   /note="HTH dtxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50944"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   154 AA;  17791 MW;  4093E2C40A79F278 CRC64;
     MKPKNSKRLD SIKAAHQSEK SSYSTRMEDY LEVISELVEL KGYATTLDIS RYMNVSAPSV
     TKMLQRLEEN KLLEYEKYHG INLTEKGTRI AIEIRQNHGI LLEFFEILGV NHETANKDAE
     GIEHHLNPKT IKQLRKFITF LKSNPKVIES FKSP
//
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