ID S2EP73_9ARCH Unreviewed; 695 AA.
AC S2EP73;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=BG20_I1724 {ECO:0000313|EMBL:EPA04309.1};
OS Candidatus Nitrosarchaeum limnium BG20.
OC Archaea; Nitrososphaerota; Nitrososphaeria; Nitrosopumilales;
OC Nitrosopumilaceae; Nitrosarchaeum.
OX NCBI_TaxID=859192 {ECO:0000313|EMBL:EPA04309.1, ECO:0000313|Proteomes:UP000014065};
RN [1] {ECO:0000313|EMBL:EPA04309.1, ECO:0000313|Proteomes:UP000014065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG20 {ECO:0000313|EMBL:EPA04309.1,
RC ECO:0000313|Proteomes:UP000014065};
RX PubMed=22461554; DOI=10.1128/JB.00007-12;
RA Mosier A.C., Allen E.E., Kim M., Ferriera S., Francis C.A.;
RT "Genome Sequence of "Candidatus Nitrosoarchaeum limnia" BG20, a Low-
RT Salinity Ammonia-Oxidizing Archaeon from the San Francisco Bay Estuary.";
RL J. Bacteriol. 194:2119-2120(2012).
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPA04309.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHJG01000325; EPA04309.1; -; Genomic_DNA.
DR RefSeq; WP_007402344.1; NZ_AHJG01000325.1.
DR AlphaFoldDB; S2EP73; -.
DR PATRIC; fig|859192.6.peg.2342; -.
DR OrthoDB; 6747at2157; -.
DR Proteomes; UP000014065; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR CDD; cd17706; MCM; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000014065}.
FT DOMAIN 300..505
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 695 AA; 78397 MW; 4D1B9CE76D8924A5 CRC64;
MSKVQTSTFT ESALSDKVKD FLTRFKDKFG SYKYVEQIDE MMPKGAKFIL VDYNDLVVEP
EIEIIFSTDP DRILNAFSRA IKEALQTRFP DYAEKIKDEV RVRLVNYPLQ RSLRQINAET
IGNITSVSGM VVRASEVKPL AKELVFICPD EHQTKVIQLK GMDVKIPIVC DNPSCKHRDF
ELKPEASKFI DFQILRLQEL PEDLPPGQLP HYIDVTIRQD LVDNARPGDR IILTGIVRVE
QESIAGITRG HSGLYRLRIE GNNIEFLGGR GSKTSRKIER EEVSPEDEKM IKTLSQSPNV
YQRLIDSFAP HIQGQSLIKE AILLLIVGST QRLLGDGSKI RGDINVFLVG DPGTAKSEML
KFCARIAPRG LYTSGRGSTA AGLTAAVVRD KTGIMMLEAG AVVLGDQGLV CIDEFDKMKP
EDRSALHEVM EQQSASIAKG GIVATLNART SILAAANPMY GKYDPFKNIT ENVNLPIPLL
TRFDLIFVVR DIPGREKDEK IARHIIELHT PQGTDKRSVI DVDILTKYLS YAKRSSPDLT
KEAEEKILEY YLQMRNVESE EMITVTPRQL EGIIRLSTAR ARLLMKDKVE EEDAERAIFL
IQSMLQDAGV DVNTGKVDLG VLQGRPRSEV SKMQLFMDVL KSMEGDNKIA VEERAFVKEL
EKTEKFTEEE ARNYIRRMLR EASIYESKPG HYNRV
//
