ID S2IYV5_MUCC1 Unreviewed; 602 AA.
AC S2IYV5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1544_10274 {ECO:0000313|EMBL:EPB82966.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB82966.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE124090; EPB82966.1; -; Genomic_DNA.
DR AlphaFoldDB; S2IYV5; -.
DR STRING; 1220926.S2IYV5; -.
DR VEuPathDB; FungiDB:HMPREF1544_10274; -.
DR eggNOG; ENOG502QR6X; Eukaryota.
DR InParanoid; S2IYV5; -.
DR OMA; HKYFATH; -.
DR OrthoDB; 5480623at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45876; FI04035P; 1.
DR PANTHER; PTHR45876:SF8; FI04035P; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014254}.
FT DOMAIN 232..385
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 396..584
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 15..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 68127 MW; 2D35379A5A90F621 CRC64;
MSLVLSANAS EGAGTLQDEL VEEKRHSRSL DLEPNARMRL HQRSASESDG IDFIAATEQK
ILPSVVASSV PTTKEETTAS NSVFSLYKKL GSPRRNRSFT SNNTKGFTSK SRASIGSAFS
SFRQPSLSNM STNTTTASLT TTTSNYINRK NRFSTPVNNP DAAMAMNPMN QSIKEEEQEK
IKKPNLLEQT GTSNLQHEIN QFSIDGFAHK YFATHKRGLF RRTVPMNELL CWTKDSIKQP
LLTSNKTLFS KDALKCFKIL QMLMNDRTRP RAFDYIESFQ TLLSCGITKG QMRDEIYVQI
CRQLNKNPKD DSIRKGWEIL CVVSVTFPPS KDLETYLHRF VQQHFNQEKN QLDILSQYVS
AKLVRICSRG ARGKVLSAAE IERAKATPFK PSVFGEPLDV IMDLQKDNTT LLIPKIVTFL
AQSVHDLNGS TSEGIFRVPG DADAVTELRI RIENGNYDST GIEDPNVPAS LLKYWLRDLA
EPLIPTDLYD DCIKYAHDKE KAIDIINSLP NINRRIALYM IRFLQDFADP QVIQHTLMNV
VNLAMVFAPN FLRCPSVNLT TIFENSKYEQ LFLKTLITEL EVDKEDCAYN EQEVIGRIKE
QV
//
