ID S2JF14_MUCC1 Unreviewed; 579 AA.
AC S2JF14;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Vacuolar protein 8 {ECO:0000256|ARBA:ARBA00026209};
GN ORFNames=HMPREF1544_12181 {ECO:0000313|EMBL:EPB81113.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB81113.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004635}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004635}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004592}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004592}.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR EMBL; KE124210; EPB81113.1; -; Genomic_DNA.
DR AlphaFoldDB; S2JF14; -.
DR STRING; 1220926.S2JF14; -.
DR VEuPathDB; FungiDB:HMPREF1544_12181; -.
DR eggNOG; KOG4224; Eukaryota.
DR InParanoid; S2JF14; -.
DR OMA; LEIVQCR; -.
DR OrthoDB; 2721872at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043495; F:protein-membrane adaptor activity; IEA:InterPro.
DR GO; GO:0071562; P:nucleus-vacuole junction assembly; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045156; Vac8.
DR PANTHER; PTHR47249; VACUOLAR PROTEIN 8; 1.
DR PANTHER; PTHR47249:SF1; VACUOLAR PROTEIN 8; 1.
DR Pfam; PF00514; Arm; 7.
DR SMART; SM00185; ARM; 9.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 7.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT REPEAT 88..130
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 129..171
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 170..212
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 211..253
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 254..296
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 295..337
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 336..379
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 579 AA; 63804 MW; E59215AC3BFC8E84 CRC64;
MGNTCSSCCC GKKSKSGLYE PLLQENEREA ITELLHFLEN RNNTNFFEGE PLRALSTLAY
SDNVDLQRSA ALAFAEITEK DVRQVGRETL DPILFLLQSH DVEVQRASSA ALGNLAVNTE
NKLLIVKLGG LDQLIRQMGS PNAEVQCNAV GCITNLATHD QNKSRIANSE ALRLLIDLAR
SKDQRVQRNA TGALLNMTHT QENRQQLVNA GAIPILISLL SSHDADVQYY CTTALSNIAV
DAVNRKKLAQ SDSKLVQYLI QLMDTKSLKV QCQAALALRN LASDEKYQLE IVQCRGLPPL
LRLLKSSFLP LILSSVACIR NISIHPANES PIIDEGFVNP LIELLSYDDN EEIQCHAIST
LRNLAASSER NKRAIVEAGA VERIKHLIKQ VPVSVKTEMT AAIAVLALSE ELKLRLLNVG
VLEILVPMTQ YYHLEVQGNA AAAIGNLSSK VKDYTPFIKA WDTPEGGLNK YLTTFTDQES
SIAFQHIGIW TIEQFAEGGC LELMAKIVGS KKIVESVARI ANNKKSAPGN DKPSVEEYPE
GDLQSLARRV LNTLHDYQVK LRSGMATEEN KKSSGHKQR
//
