ID S2JF36_MUCC1 Unreviewed; 603 AA.
AC S2JF36;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=HMPREF1544_04714 {ECO:0000313|EMBL:EPB88479.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB88479.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE123950; EPB88479.1; -; Genomic_DNA.
DR AlphaFoldDB; S2JF36; -.
DR STRING; 1220926.S2JF36; -.
DR VEuPathDB; FungiDB:HMPREF1544_04714; -.
DR eggNOG; KOG0590; Eukaryota.
DR InParanoid; S2JF36; -.
DR OMA; KHAIHQF; -.
DR OrthoDB; 5318028at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13994; STKc_HAL4_like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24343; SERINE/THREONINE KINASE; 1.
DR PANTHER; PTHR24343:SF137; SERINE_THREONINE-PROTEIN KINASE RTK1-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:EPB88479.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Transferase {ECO:0000313|EMBL:EPB88479.1}.
FT DOMAIN 273..536
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..152
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 302
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 603 AA; 68077 MW; B8233B50670367F7 CRC64;
MSTNDVTVPS SLKHSAASSH HRPADSDAYT PDRRSTGSIY SSANNISSLS ERLREVDFES
PAKIFQNKHA IHQFENVTPD ISAPGTPAIA PSTQFGYDSA ENNASSGAHT PRSQHSPSSA
HTPRSASPEY AEDGAHRKHH HKHHHHHQHA SAKPSHPATE ASSATDYTSS SARPTSAIGS
ATISRTSTPA QFVFKKPEYN SHYHHTHFHH LEKKDTIFHD LKRFFKKNQD KKKKKHLLDD
TSSVRSSGSS VYSRQSDLSF ANEFNKNLEG RYGKWGEFVG KGSGGSVRII RRNTDGKTFA
VKEFRKRAPG ENEKEYVKKV TAEFCIGSTL HNFNVIEALD IIQEGQSFYE IMEYAPNDLF
NIVMSGKMTQ DEISCCWRQL LSGVKYLQSM GIAHRDLKLD NMVLDERGVV KIIDFGCATV
IKYPFEDHVH LSKGICGSDP YIAPEQYTQK EYDARKTDLW SCGIIYICMT IRRFPWRLPR
PEKDQSYSNF VQPNNIGAEK LFKLLPRYAR PIISRILLPD PEKRCLLEDV LDDTWVKSIE
TCTPEQPAGN HPHHLLFEPS KEIMERGNII VLPAPKKEED SANNTPAVEK KKKTPDHHNR
SKK
//
