ID   S2JM74_MUCC1            Unreviewed;       514 AA.
AC   S2JM74;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Importin subunit alpha {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF1544_01733 {ECO:0000313|EMBL:EPB91411.1};
OS   Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS   agent) (Calyptromyces circinelloides).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX   NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB91411.1, ECO:0000313|Proteomes:UP000014254};
RN   [1] {ECO:0000313|Proteomes:UP000014254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the importin alpha family.
CC       {ECO:0000256|ARBA:ARBA00010394}.
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DR   EMBL; KE123909; EPB91411.1; -; Genomic_DNA.
DR   AlphaFoldDB; S2JM74; -.
DR   STRING; 1220926.S2JM74; -.
DR   VEuPathDB; FungiDB:HMPREF1544_01733; -.
DR   eggNOG; KOG0166; Eukaryota.
DR   InParanoid; S2JM74; -.
DR   OMA; QMRNMAN; -.
DR   OrthoDB; 2783331at2759; -.
DR   Proteomes; UP000014254; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR   PANTHER; PTHR23316:SF89; IMPORTIN SUBUNIT ALPHA-9; 1.
DR   Pfam; PF00514; Arm; 2.
DR   SMART; SM00185; ARM; 6.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014254}.
FT   REPEAT          174..205
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          224..266
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          59..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  57137 MW;  A619830D1684BCA8 CRC64;
     MGKPRRNSNS DHRSLYKRTS ISRTPDELIK RRVAINESLR KKHREQLITA KRFRNLNRHE
     EYESAGEEEP ASEKKDEFDE EISPYYRLST EQVEGLAKDL TSDDKTLRIV AAQHIGKFVL
     EPAKALIKYI TEGNCIETLA QMISGSNSDE QIEAAQTISN IAAGPYDLWI KSVSTVPYLI
     SLLDSDNMNL REIAAGALGN MAAEDLGDMN DEDDKVRATI RDNGAIKPLV RMLDSSDVHL
     VQSACFALAN LARGQEGQLK EFFTAGLTDK LLKNLGNADA ATEVCWVISY LTAGSEKFRE
     EVMEKGFADP LVKELANLAE QGPVVLPVLR TLGNLVGSED YLKMLAEKEA FLPKVVSLIK
     SDQRVVKKEA LWVLSNITSS QDPEIIQKLE ELDVIKHLSE LVVRGAFDIR KGAAYCIMNI
     ANHGPEHLDK LSHKQLLPAF LDLVKSQDAD MIRLGLGYIE LLLTQSPKGK EVIDNVPDCM
     EALAAVAPAP DPELFAFANK LVDQYFGESP EMQE
//