ID S2JML8_MUCC1 Unreviewed; 852 AA.
AC S2JML8;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=IPT/TIG domain-containing protein {ECO:0000259|SMART:SM00429};
GN ORFNames=HMPREF1544_03415 {ECO:0000313|EMBL:EPB89752.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB89752.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE123930; EPB89752.1; -; Genomic_DNA.
DR AlphaFoldDB; S2JML8; -.
DR STRING; 1220926.S2JML8; -.
DR VEuPathDB; FungiDB:HMPREF1544_03415; -.
DR eggNOG; KOG3836; Eukaryota.
DR InParanoid; S2JML8; -.
DR OMA; NSHYEDM; -.
DR OrthoDB; 2901153at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR24148; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR24148:SF77; IPT_TIG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 810..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 485..569
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REPEAT 649..681
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 691..723
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 52..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 605..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..792
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 94574 MW; E660121301163703 CRC64;
MTTATTTTTT TQCLSTRKLS QADLEDLLDP QVNFLPLFQD LNPGFESLYS PYSPNLDSSS
TTDTSSPPNS HYEDMAVSAE NAAAVPTSAA AAAPPPPDDF LLNYLSYNNN EIVTNSSNAP
SPCMQSNSSN NRLQIRILGV PNTGAKSRVE TQIKLCIQLM TGNEKKVQDW SYIRLSESML
ARSRLRKSQQ QQQHQHKSMD GSVATMVSDE SKVLRLEAQV VCASSTDQPI RMCVGCVRRE
RKRAERTKDG KHKGDILPED IEAERDRILL FNCSPMINFS SGDAILPTRI TCYCRHHNEK
VGFRICFSMK NNKDEIIANG ISPPIMITDD HKSSKQKTAR KRSRQEDDQL TISRPDTPAP
SRKNSISIDP IQPPTDIADD NMESTTPTSL EFINSGISVM TNSNSNSSSN IYSDFFPPPP
ASLSFNVPME LPTPQPQYSP EEDTVASTEE AWPFNRRRRT TSGYASTDDR AMTSFLDDLN
PVVVVPQLER LVPAQGPTYG GVEVTLLGSG FYRGLTCLFG EHAATTVYWN PNTIVCILPP
AAHTGPVVVS FKEHPLVLEG QDVAIFTYYD ASDQALLELA LQVVGLKMTG KLHDAKHVAM
RIVQGGEPSQ QQQQQQQQQQ QQQHQQHQQA VLDAIEYANH PDLSLVNASG QTLLHLSVML
GNEELVKAII NAYAYRPTED KQKLLNTQDK NEMTALQYAC QMKSMEIIRI LLHAGANPTS
LDSAWLKKSC AAEDIVDLLD LYTTSNHIKR KPLSRRNSSI KSHMMHRFHS LSNTSTESIP
HGSGTDSKHT PSMESDGLGL VRQKSDRRLY LFWLPVLMLA VGLLFVQMFG QPALLRPILE
LLPNSHRIPL SA
//
