ID S2JQJ7_MUCC1 Unreviewed; 372 AA.
AC S2JQJ7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=protein-histidine N-methyltransferase {ECO:0000256|ARBA:ARBA00012533};
DE EC=2.1.1.85 {ECO:0000256|ARBA:ARBA00012533};
GN ORFNames=HMPREF1544_11239 {ECO:0000313|EMBL:EPB82035.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB82035.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METTL18
CC family. {ECO:0000256|ARBA:ARBA00038126}.
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DR EMBL; KE124134; EPB82035.1; -; Genomic_DNA.
DR AlphaFoldDB; S2JQJ7; -.
DR STRING; 1220926.S2JQJ7; -.
DR VEuPathDB; FungiDB:HMPREF1544_11239; -.
DR eggNOG; KOG2920; Eukaryota.
DR InParanoid; S2JQJ7; -.
DR OMA; ADVKFQM; -.
DR OrthoDB; 276605at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF39; HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254}.
FT REGION 199..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..237
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 41863 MW; 63CD64D9C5D07F3A CRC64;
MAFKFNFTNE DLDLEDNEEN QQLESSLHDL SIDEKKEELN QIPSREYDIL SSPLPSVIQA
DILHIPNLEK TLMKRTLADV KFQMAEQDNL VDDTQEADVV NMLNLSGNTD LIKGVYEGGF
KTWECSIDMV QYLSGLPEEQ ITNKRVLELG CGSSLPSLYL LSHSNTNRVD VQDYNDQVIR
YITIPNILLN TVLTVQEPSA AKTEENQEPS DSEVDSEDDE EEEEEDDEEG KRIEEDVDTC
DAEAEIAGEN IPTMLQQLSS RTRAFVGDWS SLPAQLNVDH EKYDMIVTSE TIYAEHALPD
LISVFQKALK KPDGVCYVAA KTVYFGVGGG ILPFCNLLVK TQDADGDKLT YEKVFESAST
VKREILKVSW DL
//
